Opinion
Podcast
Author(s):
In this MEDcast episode, Drs Soloman, Sharobeem, Boone and Feldman discuss the use of step therapy in rheumatoid arthritis, how step therapy was intended to be used, how it is actually used, and challenges and solutions to its use.
To watch the video series component of this episode, click here.
00:06 Welcome and introduction
01:43 Treatment landscape of rheumatoid arthritis
08:30 Use of TNFi in rheumatoid arthritis
12:33 Switching from TNFi in rheumatoid arthritis
14:33 Step therapy in medicine
20:16 Variations in the use of step therapy between states
22:40 Outcomes with step therapy
26:25 Step therapy legislations
27:09 Administrative burden of step therapy
28:28 Safe step act
29:19 CSRO map tool for step therapy
32:20 Processing of exceptions to step therapy protocols
33:44 Step therapy in rheumatoid arthritis
36:45 Impact of staying on ineffective RA treatments
38:59 Personalization of medicine in RA
41:20 Use of molecular signature response classifier (MSRC) in RA
42:58 Step therapy and use of molecular signature response classifier (MSRC) test in clinical practice
46:12 Advice for patients and HCPs in navigating step therapy protocols
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