Cushing's Syndrome Pharma Focus: Cortisol-Inhibiting Medications

Please click on the link provided in the title of each medication to access the third-party site of the resource.

Ketoconazole

Brand Names: Nizoral, Extina, Xolegel, Kuric

Type: Tablets, 200 mg (oral administration)

Indication: No FDA-approved indication

Mitotane

Brand Name: Lysodren

Type: Tablet, 500 mg (oral administration)

Indication: Treatment of inoperable adrenal cortical carcinoma of both functional and nonfunctional types

Aminoglutethimide

Brand Name: Cytadren

Type: Tablet, 250 mg (oral administration)

Indication: Suppression of adrenal function in selected patients

Metyrapone

Brand Name: Metopirone

Type: Capsule, 250 mg (oral administration)

Indication: Diagnostic drug for testing hypothalamic-pituitary ACTH function