Rhinocerebral Mucormycosis in Woman with Uncontrolled Diabetes


What's the connection between type 2 diabetes and rhinocerebral mucormycosis? Here's a case in point.

A 67-year-old woman with type 2 diabetes presents with delirium secondary to diabetic ketoacidosis. She also has headache, facial and left eye pain, nasal congestion, and blurry vision. A CT scan shows general swelling of the turbinates with maxillary congestion and air-fluid level on the ethmoidal sinus. The diagnosis is rhinocerebral mucormycosis.


Which of the following statements about this fungal infection is/are true?

Mucormycosis often occurs in patients with DM, especially in the presence of diabetic ketoacidosis.
Mucormycosis may be the first manifestation of undiagnosed diabetes.
Rhinocerebral mucormycosis is the most common form of mucormycosis in patients with DM.
Elevated blood glucose is a predisposing factor.
The incidence appears to be rising, with rising numbers of patients with uncontrolled DM.
All of the above are true.
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