The Microbiome’s Effect on Psoriatic Arthritis
Epidemiological evidence points to an intimate relationship between intestinal inflammation and joint inflammation, such as psoriatic arthritis.
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Endo News Roundup: Managing HbA1c & CV Risks
New studies highlight which T2DM meds help reduce CV risks and, for metformin failure, the benefits of early intervention & a promising drug combo.
Rethink Optimal Insulin Dose Calculations
To achieve target glucose control, a new study looks at the role of meal composition, including fat and protein, when calculating insulin doses.
How Fats Impact Insulin Resistance, T2DM
Using findings from 100 RCTs, researchers summarize the effects of different dietary fats and carbohydrate on insulin resistance and type 2 diabetes.
Reproductive History and Type 2 Diabetes Risk
A prospective cohort analysis suggests that the length of a woman’s reproductive period has an impact on risk of type 2 diabetes.
Glucose-Lowering Drugs, Diabetes, & CV Mortality
A study examined the risk of CV or all-cause mortality associated with glucose-lowering drugs taken alone or in combination for type 2 diabetes.
Apremilast Improves Joint and Skin Involvement in Psoriatic Arthritis
Apremilast may represent a new oral treatment option for patients with psoriatic arthritis (PsA) and current skin involvement, according to a new study.
Elderly Psoriasis Patients Show Poor Adherence to Biologics
A new study finds that slightly more than one-third of the patients were adherent to their index biologic and almost half discontinued within 12 months of initiation of therapy.
Secukinumab Improves PROs in Psoriatic Arthritis
Treatment with the monoclonal antibody secukinumab not only improves responses among psoriatic arthritis (PsA) patients, but also results in clinically meaningful improvements in global disease activity, study shows.
Psoriasis Patients Make Personalized Treatment Tradeoffs
The choice of treatment for psoriasis is highly personal. Some psoriasis patients are willing to trade decreased safety for increased effectiveness or increased convenience.
Psychological Barriers to Insulin Treatment
Why do adolescents with type 1 diabetes fail to meet the international HbA1c treatment target? What can be done to overcome treatment barriers?
Targeting Insulin Doses in Type 2 Diabetes
Investigators explored the use of bedtime and morning blood glucose values to address postprandial control issues in patients with type 2 diabetes.
Engaged Patients Use Less Healthcare
Patient self-monitoring of DMARD therapy can lead to significant reductions in health care use, researchers show.
Physical Activity Impacts Diabetes Prevention
Follow-up data from the landmark Diabetes Prevention Study examined the role of physical activity in diabetes prevention.
Stem Cells Transformed in Type 1 Diabetes
Could a patient’s own stem cells be used to create insulin-secreting cells, even if that patient has type 1 diabetes?
Beyond Basal Insulin in Type 2 Diabetes
Several studies presented at ADA 2016 discussed going beyond basal insulin treatments for patients with type 2 diabetes.
Benefits of Continued Cardiorespiratory Fitness
A 20-year study examined the long-term effect of cardiorespiratory fitness on risk of developing prediabetes or diabetes.
Aging and Beta Cell Function
Aging may be beneficial to diabetes patients. Recent findings suggest a cellular aging process may, unexpectedly, enhance insulin secretion.
Endo News Roundup: Promising Diabetes Therapies
Three new studies highlight promising diabetes drug treatments to help patients who struggle with severe hyperglycemia.
Insulin Plus Metformin in Type 2 Diabetes
Does insulin in conjunction with metformin have the potential to reduce all-cause mortality in patients with type 2 diabetes?
Risk with Basal Insulin in Older Diabetics
Researchers investigated the risk of hospitalization or death in older patients with type 2 diabetes initiating basal insulin treatment.
Another Benefit of Long-term Weight Loss
Researchers measured cognitive function in diabetic patients to study the effects of losing weight and increasing physical activity on brain health.
Cost Analysis: Insulin & Other Antihyperglycemics
A new study examines trends in expenditure and price of insulin and other antihyperglycemic medications in the United States from 2002 through 2013.
Is Metformin Still Top Drug for Type 2 Diabetes?
A new study evaluated the comparative effectiveness and safety of monotherapy and selected metformin-based combinations for type 2 diabetes.
Sleep Deprivation Affects Insulin Sensitivity
Adult studies show a link between sleep deprivation & increased CV factors, plus higher obesity & diabetes risk. Does the same hold true for teens?
Reversing Oxidative Stress and Inflammation in Diabetes
Subcutaneous insulin infusion is the gold standard for type 1 diabetic therapy, but this approach may induce glycemic variability in some patients.
New Insulin Versions on the Horizon
New prefilled and reusable insulin delivery devices will require education and training for patients, significant others, and caregivers.
CardioScience Update, 4 New Studies
Highlights of four recent studies in hypertension, heart failure, preeclampsia expose vulnerable populations.
Type 2 Diabetes and Depressive Symptoms
Two recent studies examined the link between depressive symptoms in adolescence and type 2 diabetes.