Brain Changes from Small Vessel Disease Demonstrated by Impaired Gait Speed
Brain changes that occur as a result of small vessel disease negatively effect gait in senior patients, research shows.
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Measuring the Value of How a Patient “Feels”
How a patient feels may be a better indicator of the effectiveness of treatment than actual disease activity, researchers say.
More Methotrexate Not Always Better
A higher initial dose of methotrexate is not always associated with better clinical outcomes for newly diagnosed rheumatoid arthritis patients, a study shows.
HDL Cholesterol Improves in RA with Anti-inflammatory Treatment
Anti-inflammatory treatment in rheumatoid arthritis patients, especially with infliximab added to methotrexate, improves HDL function and may potentially reduce cardiovascular risk, a study shows.
Controlling RA Flares During Pregnancy
RA patients with low disease activity in the first trimester of pregnancy, are likely to have low disease activity or reach remission by the third trimester.
Immune-Related Adverse Events Rise with Immune Checkpoint Inhibitors
Rheumatologists are likely to encounter a wide variety of immune-related adverse events as use of immune checkpoint inhibitors expands.
Periodontal Disease and RA Connection No Longer a Mystery?
The association between periodontal disease and rheumatoid arthritis has been well established in studies, but now researchers describe a mechanism that could explain this association.
Autoimmune Bullae-Forming Skin Disease Associated with IgE Autoantibodies
Researchers have made an important discovery that may lead to new treatment for patients with bullous pemphigoid, a chronic autoimmune skin disease causing blisters.
Habitual Weight-Bearing Exercise Best for Bone Strength in Elderly
The elderly can build lower limb bone strength with habitual weight-bearing exercises, not medium or low impact exercise, research shows.
Hypersensitivity Low in RA Biologics
Some biologics produce hypersensitivity reactions more than others, but for most, the events are low, researchers report.
Methotrexate Underutilized in RA
Methotrexate is "dramatically" underutilized, prescribed at suboptimal levels, prescribed for too short of periods and is not administered correctly, researchers report.
Poor Awareness and Confusion Hamper Patient Reporting of Adverse Drug Reactions
Patients fail to report adverse drug reactions due to poor awareness, but when they do speak up, it’s to prevent others from suffering.
CPDD: VA Study Confirms Most Classic Associations
Study supports associations between crystal deposition disease, rheumatoid arthritis and osteoporosis.
Missed Risk Factors in Osteoporosis Screening Crucial in Diagnostics
The expanded National Bone Health Alliance definition of osteoporosis may better identify those at elevated fracture risk.
Adalimumab Improves Uveitis, Studies Show
Adalimumab improves function and quality of life for patients with uveitis, shows a study presented at 2015 ACR/ARHP.
Sarilumab as Safe as Tocilizumab in RA Drug Trial
IL-6 inhibitors sarilumab, an investigational drug, and tocilizumab, an established treatment in RA, are equally safe, shows two studies presented at ACR/ARHP 2015.
Combined Treatment Leads to Sustained Remission in RA
Certolizumab pegol with methotrexate leads to impressive outcomes for early rheumatoid arthritis patients, shows study presented at 2015 ACR/ARHP.
Do You and Your Patients Agree on Treatment Goals?
Research highlights a need for closer partnerships between physicians and patients to set shared treatment goals.
Superior RA Outcomes for JAK1/JAK2 Inhibitor Baricitinib
Patients with early RA see improvements in symptoms with baricitinib 4 mg monotherapy producing larger, rapid improvements with higher rates of clinical remission as compared to MTX monotherapy.
Corticotropin Injection in Lupus Leads to Significant Improvements
Despite missing the primary endpoint, trial of repository corticotropin shows improved key measures.
Efficacy Lies in Both Sarilumab and Methotrexate in RA
Sarilumab with csDMARDS are safe and effective in rheumatoid arthritis patients after TNF failure or intolerance.
DDW 2011: Rifaximin Reduces SBP Risk, Improves Transplant-Free Survival
Intestinal decontamination with rifaximin prevents spontaneous bacterial peritonitis and improves transplant-free survival in cirrhotic patients with ascites.
DDW 2011: Study Examines Colonoscopy Bleeding Risk with Clopidogrel vs. CV Risk Without
Cardiovascular risks associated with discontinuing clopidogrel before elective colonoscopy exceed the risks of post-polypectomy bleeding.
DDW 2011: STEPS Study Shows Promising Results for Patients with Short Bowel Syndrome
GLP-2 analog teduglutide reduces the need for parenteral support in patients with short bowel syndrome-intestinal failure.
DDW 2011: Adding Telaprevir to Standard Therapy Increases Sustained Virologic Responses in HCV
Results from the REALIZE study show that combination treatment with telaprevir is superior to standard treatment for patients with hepatitis C virus infection.
DDW 2011: High-intensity Sports Increase Risk of Functional GI Disorders
High-intensity athletes report more functional gastrointestinal disorders than athletes who engage in lower-intensity sports.
DDW 2011: Should Old Age Disqualify Patients from Receiving Weight Loss Surgery?
Age is less important than BMI, cardiovascular health, diabetes, and other considerations when evaluating elderly patients for bariatric surgery.
DDW 2011: Robust Reductions in Serious Liver Complications Likely with New HCV Agent
Combination treatment with boceprevir produces a significant reduction in incidence of serious liver complications in patients with hepatitis C.
DDW 2011: Attention to Diet May Lower Gallstone Formation Risk during Pregnancy
High consumption carbohydrates, starch, and fructose may increase the risk of developing biliary sludge and stones during pregnancy.
DDW 2011: Despite High Risks, Vaccination Rates Are Low in Chronic Liver Disease Patients with Diabetes
Low vaccination rates among patients with CLD and diabetes have grave public health implications.