The HCPLive diabetic macular edema page is a comprehensive resource for clinical news and insights on DME. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for the leading cause of blindness, and more.
May 13th 2024
At the end of ARVO 2024, Srinivas R. Sadda, MD, became the organization's president for the 2024-2025 year. He spoke to HCPLive about his expectations for the next year in eye care.
Recent Trial: Ranibizumab Did Not Prevent New Macular Atrophy in Cases of Neovascular AMD
Whether injected monthly or according to a TREX regimen, ranibizumab did not have a statistically significant effect on the development of new macular atrophy in eyes with neovascular AMD.
Study Disputes Anti-VEGF Injection Link to Long-Term Intraocular Pressure Increase
During follow-up periods ranging from six months to 10 years, no increase in IOP over time was found in AMD or DME patients who received intravitreal injection of an anti-VEGF agent, no matter how many injections they received.
Studies Conflict on Ranibizumab's Stroke Risk
In a new study, stroke occurred in 6.6% of the ranibizumab-treated group, compared with 7.0% of the controls matched by sociodemographic factors and comorbidities and 6.7% of the controls matched by sociodemographic factors only. These differences were not statistically significant.
Antibody Development an Obstacle in Treating Uveitis with Humira
A Spanish research team found an association between testing positive for antibodies to adalimumab (Humira) and a worse outcome of uveitis, but only in those who tested positive permanently. They also found that this association correlated with undetectable trough levels of Humira.
No Tool Yet To Identify Visual Impairments after Strokes
Despite the fact that two thirds of stroke survivors could suffer from a visual impairment, nearly half of stroke units do not even assess vision. A recent report suggests that more must be done to assess the outlook for vision in stroke survivors.
Mediterranean Diet May Deter Macular Degeneration
A recent study joins an ever-deepening well of data about the health benefits of the Mediterranean diet, including its risk-reduction potential for age-related macular degeneration. AMD is the leading cause of blindness in the developed world.
Diabetic Macular Edema Study: Ozurdex Outperformed Avastin, but Not Without Drawbacks
Monthly Avastin injections and quarterly Ozurdex injections produced equivalent improvements in best-corrected visual acuity after 7 months. However, Ozurdex reduced central subfield thickness nine times more than Avastin did, though it was associated with elevated intraocular pressure.
Patients See Benefits of Technological Advances in Ophthalmology
As with most surgical advances, new potential procedures in ophthalmology pose their fair share of risks. However, if those risks can be overcome the rewards to patients can make a significant difference in their quality of life.
Finding New Uses for ARGUS Technology in Age-Related Macular Degeneration
As a retinal implant, the ARGUS II technology has shown early benefits for patients with retinitis pigmentosa. A new study from the United Kingdom is examining its benefits in patients with the dry form of age related macular degeneration.
Weighing Safety Risks and Efficacy of New Vitrectomy Procedure Option
As with all new technologies for surgical procedures, there will be questions to be answered about the safety for hypersonic vitrectomy. While human trials have not started yet, there are good indications in cadaveric and animal studies.
High-Fat Diets Alter Gut Microbiota, Leading to Increased Choroidal Neovascularization
Research using mouse models demonstrated that a high-fat diet increased intestinal permeability, which led to increases in circulating and local inflammatory cytokines, and increased choroidal neovascularization.
Subretinal Gene Therapy Improves Vision in Patients with Wet Age-Related Macular Degeneration
Treatment with recombinant adeno-associated virus vector gene-therapy was shown to be safe and potentially effective in a small test group of patients with neovascular age-related macular degeneration.
New Telemedicine Screening Program Looks to Improve Treatment of Diabetic Retinopathy
As part of their overall health management, patients with diabetes are encouraged to undergo annual eye exams. While not all patients follow this direction, research is being done to better improve their eye health by working with their general practitioners.
Taking Treatment from the Lab to the Clinic: Rishi Singh from Cleveland Clinic
In many, if not most cases, there can be a break in the chain between researchers and the doctors they are developing treatments for. When that divide does not exist it can mean more direct access for doctors and patients to the latest treatments even in the development stages.