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Opioid-induced Constipation
FDA Approves Opioid Agonist Oliceridine
August 07, 2020
Article
The indication limits the new opioid to clinical setting use—no take-home prescriptions.
Introducing Painkiller: A History of Crisis
March 01, 2020
Article
The expert-led narrative series will seek to answer when and how the development of opioids led to a public health crisis.
FDA Approves Tegaserod Reintroduction for IBS with Constipation
April 01, 2019
Article
Originally approved in 2002, tegaserod (Zelnorm) was withdrawn in 2007 due to potential safety concerns.
Synergy Pharmaceuticals Submits NDA for IBS-C Drug Plecanatide
March 27, 2017
Article
Pharma submits sNDA for IBS-C drug plecanatide.
Chronic Idiopathic Constipation Gets New FDA Approved Treatment
January 19, 2017
Article
The FDA today approved constipation remedy plecanatide.
Promising Results for Experimental Irritable Bowel Syndrome Drug
December 09, 2016
Article
Patients suffering from irritable bowel syndrome with constipation (IBS-C) may benefit from a new drug, plecanatide, making its way through the approval pipeline.
Five Categories of Lower Gastrointestinal Functional Bowel Disorders in Revised Rome IV Criteria
May 24, 2016
Article
The new Rome IV criteria classify the functional bowel disorders into five distinct categories, including irritable bowel syndrome (IBS), functional constipation, functional diarrhea, functional abdominal bloating/distention, and unspecified functional bowel disorder. A new category for opioid-induced constipation, which is distinct from the functional bowel disorders, has been added.
Rome IV Criteria Get Specific about Functional Gastroduodenal Disorders
May 24, 2016
Article
Rome IV updates include more specific definitions and diagnostic criteria for functional gastroduodenal disorders such as functional dyspepsia, belching disorders, and nausea and vomiting disorders.