eAbstract: Efficacy and Safety of Azithromycin 1.5% Eye Drops for Purulent Bacterial Conjunctivitis in Pediatric Patients

March 9, 2010

Article

The results of this study found that azithromycin 1.5% eye drops are more effective than tobramycin for treating bacterial conjunctivitis.

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Efficacy and Safety of Azithromycin 1.5% Eye Drops for Purulent Bacterial Conjunctivitis in Pediatric Patients

Journal: The Pediatric Infectious Disease Journal (March 2010)

Authors: Bremond-Gignac D, Mariani-Kurkdjian P, Beresniak A, et al.

Purpose: To evaluate the safety and efficacy of azithromycin 1.5% eye drops for the treatment of purulent bacterial conjunctivitis in children.

Results: Compared to tobramycin 0.3%, with 1 drop every 2 hours for 2 days and then 4 times daily for 5 days, azithromycin 1.5% eye drops twice daily for 3 days “provided a greater bacteriologic cure on day 3 than did tobramycin (P < 0.001) and eradicated bacteria that were defined as resistant, using classical antibiogram.” The authors conclude: “azithromycin 1.5% eye drops leads to a rapid clinical and microbiological cure.”