Letrozole as a Treatment of Endometrial Cancer

December 31, 2009

Letrozole is a drug that blocks estrogen production, which causes endometrial cancer to grow in some cases. This study will examine whether the investigators may be able to predict which patients might benefit from Letrozole treatment by studying the different forms of the estrogen-receptor molecule that exist within the cancer tissues.

Study Type: Interventional

Age/Sex Requirement: 40 years+ (female)

Sponsor: University of California, Davis

Purpose: Letrozole is a drug that blocks estrogen production, which causes endometrial cancer to grow in some cases. This study will examine whether the investigators may be able to predict which patients might benefit from Letrozole treatment by studying the different forms of the estrogen-receptor molecule that exist within the cancer tissues. The study will be monitoring changes in estradiol level and apoptosis before treatment with Letrozole and at around 3 weeks following treatment.

Click here to learn more about this clinical trial.