Letrozole as a Treatment of Endometrial Cancer
Letrozole is a drug that blocks estrogen production, which causes endometrial cancer to grow in some cases. This study will examine whether the investigators may be able to predict which patients might benefit from Letrozole treatment by studying the different forms of the estrogen-receptor molecule that exist within the cancer tissues.
Study Type: Interventional
Age/Sex Requirement: 40 years+ (female)
Sponsor: University of California, Davis
Purpose: Letrozole is a drug that blocks estrogen production, which causes endometrial cancer to grow in some cases. This study will examine whether the investigators may be able to predict which patients might benefit from Letrozole treatment by studying the different forms of the estrogen-receptor molecule that exist within the cancer tissues. The study will be monitoring changes in estradiol level and apoptosis before treatment with Letrozole and at around 3 weeks following treatment.
