Presentation of Generalized Pustular Psoriasis (GPP) in the Hospital


Dermatologists Drs Tina Bhutani and Scott Boswell discuss how patients with generalized pustular psoriasis (GPP) typically present in the hospital.

This is a video synopsis/summary of a panel discussion involving Tina Bhutani, MD; J. Scott Boswell, MD; and Kanya Oul, RN.

In the discussion, the challenges of diagnosing Generalized Pustular Psoriasis (GPP) are highlighted, with a focus on the experiences of patients who often face misdiagnosis. The dermatologist acknowledges a patient’s typical journey, where initial symptoms are mistaken for conditions like Stevens-Johnson syndrome due to a lack of training in severe skin diseases among emergency medicine providers. Patients may go undiagnosed for years, receiving treatments for infections instead.

Key signs of GPP, including monomorphic sterile pustules and erythrodermic skin, are discussed, emphasizing the importance of recognizing that pus does not always indicate infection but rather an immune system reaction. The patient’s description of her symptoms, including fever and extreme edema, highlights the systemic nature of GPP beyond skin manifestations. Laboratory values such as elevated inflammatory markers and white blood cell count further underscore the inflammatory and systemic nature of the disease.

The conversation sheds light on the need for heightened awareness among healthcare providers to consider GPP as a systemic inflammatory disease, not merely a skin condition. Through patient testimonies and medical insights, the discussion aims to improve early diagnosis and management of GPP, reducing the burden of misdiagnosis and enhancing patient outcomes.

Video synopsis is AI-generated and reviewed by HCPLive editorial staff.

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