Aspirin Linked to Greater Macular Degeneration Risk
A large population study in Taiwan found regular use of aspirin for prevention of cardiac events increased risk for age-related macular degeneration.
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A Drop of Ophthalmic a Day Could Keep Ptosis Surgery at Bay
A daily drop of oxymetazoline ophthalmic could avert surgery for acquired ptosis, according to new findings.
Cataracts Linked to Depressive Symptoms in Elderly
Cataracts, but not AMD or glaucoma, were associated with an increased risk of depressive symptoms in the elderly in a prospective long-term study.
The Eyes Are Windows into Sport-Related Concussion in Adolescents
Pupillary light reflex metrics could provide an objective biomarker to determine whether an adolescent athlete has suffered a concussion.
Managing Dwindling Medication Supplies for COVID-19
The shortages highlight heavy US dependence on bulk drug ingredients.
Hydroxychloroquine Speeds Up COVID-19 Recovery Over Placebo
Findings of a placebo-controlled trial show the addition of hydroxychloroquine to treatment leads to a quicker recovery.
Appendectomies and the Development of Parkinson's Disease
In a study presented at Digestive Disease Week 2019, results indicated the risk of developing Parkinson's disease was 3 times higher in patients who had appendectomies.
Intrahepatic Cholestasis of Pregnancy linked to NAFLD
A study presented at DDW 2019 found that women with intrahepatic cholestasis of pregnancy were 5.7 times more likely to have a NAFLD diagnosis
Endoscopic Sleeve Gastroplasty 5-Year Outcomes
A study presented at DDW 2019 found that endoscopic sleeve gastroplasties found significant and sustainable weight loss among patients 5 years after surgery.
Fecal Microbiota Transplant Could Aid Weight Loss
Study presented at DDW 2019 found that transplantation of gut microbes from lean donor could aid weight loss in obese, metabolically healthy recipients.
Multifaceted Intervention Triples HCV Screening Rate
Using education, EHR alerts, and increased clinic capacity, investigators increased HCV screening of baby boomers from 10.1% to 34.6%.
DAAs Enable HCV-Infected Heart, Lung Transplants
Short-course, "post-exposure" direct-acting antivirals enabled successful transplantation of HCV-infected hearts and lungs to uninfected recipients.
DAA Treatment for Children with HCV?
Currently, DAAs lack FDA approval for hepatitis C treatment in children under 12 years, but pediatricians call for their approval.
Cash Incentives, Peer Support May Not Incentivize HCV Treatment
A randomized trial compared cash incentives, peer support, and usual care for increasing rate of HCV treatment among HCV/HIV infected people who use drugs.
Insurance Coverage Factors into ER Care of Pulmonary Patients
Economic factors can influence ER department patient disposition, despite prohibitions against such practice.
Study of DAA for HCV Finds High Adherence, Lower Costs
A study of DAA treatment of HCV in the US finds high adherence and effectiveness at less cost than when the antivirals were introduced.
Air Pollution-Related ER Visits Vary by Age, Respiratory Illness
The CDC conducted the first nationally relevant study of associations between air pollutants and ER visits across patient demographics and conditions.
Concerns of Efficacy, Safety Are Barriers to DAA Treatment for Veterans
Investigators identified reasons veterans might decline or not adhere to HCV treatment and proposed ways to optimize treatment.
Shortened Treatment Found for Multidrug-Resistant Tuberculosis
A new trial finds a drug regimen for multidrug-resistant TB can be substantially shorter than the 20 months currently recommended by the WHO.
Fatty Liver Found More Often with HCV Than HCV/HIV
Steatosis was found more often with HCV monoinfection than with HCV/HIV and more commonly detected with imaging than with biopsy.
HCV Increases Mortality in Dialysis Patients
HCV infection was found to be an independent and significant risk factor for death in patients with chronic kidney disease on maintenance dialysis.
Gene Predicts Recovery from Decompensated HCV Cirrhosis
A gene linked to risk for steatosis predicted likelihood of patients with sustained virologic response recovering from decompensated HCV cirrhosis.
HCV Treatment Effective in "Real World" HIV Coinfected Patients
Sustained virologic response rates were high among HCV/HIV coinfected patients with early treatment discontinuation the only factor associated with lower SVR rate.
Long-term Consequences of Sustained Virologic Response for HCV Infection
Investigators recognize sustained virologic response to DAAs for hepatitis C infection as valid clinical endpoint of treatment, but question how it relates to long-term health.
Cancer Patients with Treated HCV Suitable for Chemo Trials
After demonstrating success of direct-acting antivirals for HCV in cancer patients, investigators call for their eligibility to participate in chemo trials.
Eliminating HBV, HCV 'No longer pipe dreams'
Scientists at the Task Force for Global Health describe what is needed to eliminate HBV and HCV as public health threats.
Anticipated HCV Vaccine Could Help Achieve Eradication Goals
Models indicate that a vaccine with just 30% efficacy would significantly reduce HCV transmission if provided to persons at high risk of infection from injecting drugs.
Disease-Modifying Therapies of MS Reduce Persistent Disability Risk
Disease-modifying therapies for relapsing-remitting MS were shown to reduce risk of conversion to secondary progressive MS.
Treating HCV in Cancer Patients Opens Chemotherapy Options
First prospective study of direct-acting antiviral treatment of HCV in cancer patients finds that it is safe, efficacious, and that it can open options for chemotherapy.
Multiple Sclerosis Stem Cell Transplant Compared to Disease-Modifying Therapy
In a rare clinical trial, stem cell transplantation appeared to provide greater protection against MS progression than DMT.