Kenneth Bender, PharmD, MA

Whole genome sequencing suggests both common and rare variants contribute to early onset drusen maculopathy.

Pharmacovigilance studies sifting through FDA adverse event reports confirm ocular side effects from PCSK9 inhibitors are infrequent and minor.

Higher tolerance of retinal fluid in neovascular AMD corresponded to needing fewer anti-VEGF treatment injections for same visual outcomes.

Finnish population study attributes reduction in visual impairment from AMD to improved diagnostic tools, earlier diagnoses, and new therapies.

The oral Janus kinase 1 inhibitor abrocitinib produced similar outcomes to dupilumab in a placebo-controlled comparison for atopic dermatitis.

Investigators conducted what's believed to be the largest prospective observational studies of response to changing treatment regimens in patients with lupus nephritis who do not respond to initial, first-line therapy.

Pegcetacoplan, an investigational complement C3 inhibitor, demonstrated superiority to C5 inhibitor, eculizumab, for paroxysmal nocturnal hemoglobinuria.

A head-to-head assessment of the intravenous treatment options found greater efficacy for acetaminophen, supporting it more against the adverse effect-associated diclofenac.

Brain function improved with hydroxyurea treatment of sickle cell disease in prospective study with cerebrovascular and neuropsychologic measures.

Vascular electrical stimulation therapy was associated with reduction in vaso-occlusive symptoms.

Surgeons recommend measures to reduce complications from cholecystectomy and splenectomy in patients with sickle cell disease.

Two gene therapy techniques in separate, concurrently published trials demonstrate clinical success in mitigating monogenic hemoglobinopathies.

Elevated tricuspid reguritant velocity levels as a biomarker for SCA severity also marks response to disease modifying treatments.

The SGLT2 inhibitor demonstrated possible erythropoietic effects in type 2 diabetes patients.

Elevated cardiac troponins during hospitalization for influenza is associated with heightened risk of mortality after hospital discharge.

Influenza vaccination not only protects against the flu, but could lessen the severity of COVID-19.

Point of care test-and-treat strategy for influenza improves efficiency of hospital triage and the clinical outcomes for patients with acute respiratory illness.

Tofacitinib-methotrexate trial extended as first randomized controlled trial of tofacitinib monotherapy for psoriatic arthritis.

Oseltamivir and zanamivir are compared in acute treatment of patients with severe influenza type-A H1N1 in China.

Largest study of multiple health indicators over time finds widening disparities in health by race, despite increased targeted funding.

The first case report of COVID-19 reinfection in a patient with beta thalassemia major describes absence of symptoms and two-month interval between positive PCR tests.

A review of studies seeks the prevalence, determinants and outcomes of iron deficiency anemia in expecting mothers with sickle cell disease.

A large population study in Taiwan found regular use of aspirin for prevention of cardiac events increased risk for age-related macular degeneration.

A daily drop of oxymetazoline ophthalmic could avert surgery for acquired ptosis, according to new findings.

Cataracts, but not AMD or glaucoma, were associated with an increased risk of depressive symptoms in the elderly in a prospective long-term study.

Pupillary light reflex metrics could provide an objective biomarker to determine whether an adolescent athlete has suffered a concussion.

The shortages highlight heavy US dependence on bulk drug ingredients.

Findings of a placebo-controlled trial show the addition of hydroxychloroquine to treatment leads to a quicker recovery.

In a study presented at Digestive Disease Week 2019, results indicated the risk of developing Parkinson's disease was 3 times higher in patients who had appendectomies.

A study presented at DDW 2019 found that women with intrahepatic cholestasis of pregnancy were 5.7 times more likely to have a NAFLD diagnosis