Christoph Correll, MD: New Paliperidone Palmitate Data for Schizophrenia
New 3-year analysis shows a significant rate of patients were able to avoid relapse or hospitalization while receiving the long-acting injectable.
Dementia More Closely Linked to Infections than Autoimmune Diseases
A nationwide cohort study shows individuals with a history of infection are at a nearly 50% greater likelihood of dementia development in older age.
Pharmacist Biosimilar Substitution Program Provides Significant Cost Savings
A program from the American Oncology Network shows promise to introducing cost-efficient biosimilar substitution opportunities to prescribers and payors.
Research Shows High Consistency of Biosimilars to Prominent Biologics in the US
An analysis from Taiwan suggest immunogenicity differences are limited between biosimilars approved by the FDA and their reference biologic products.
Cynthia Levy, MD: Seladelpar for PBC and the IDEAL Trial
The University of Miami study previews the upcoming phase 3 trial and what the investigative seladelpar may provide patients with primary biliary cholangitis.
Cynthia Levy, MD: Primary Biliary Cholangitis Burden & Treatment Options
The phase 3 seladelpar investigator discusses the current landscape of care available for patients with PBC.
Eye-Tracking Device Predicts Expert Autism Diagnoses
A recently authorized device for autism detection showed promising accuracy in research across US specialty clinics. The lead author shares his thoughts on a new podcast.
Pulmonary Embolism 101 with Parth Rali, MD
In the latest episode of Lungcast, the diagnosis, classifciation and treatment of PE—namely blood clots—is comprehensively dissected by the Lewis Katz School of Medicine clinician and investigator.
US Life Expectancy Decreased Significantly Relative to Global Rates
An analysis of life expectancy growth since the 1930s suggest more than 50 countries have surpassed the US—with the gap compared to the leading countries widening in that time.
6 Drug Classes and Vaccine Candidates for Hepatitis C
A number of innovative, virus-targeting agents are under investigation to treat HCV—or even prevent it.
COVID-19 Cases Are Climbing, with Donald Alcendor, PhD
Alcendor discusses the recent uptick in cases and hospitalizations, as well as the latest variants of concern and developments in 2023-24 booster doses.
Single-Dose Psilocybin Significantly Improves Major Depressive Disorder Symptoms Within 8 Days
New phase 2 data adds to the growing interest in the psychedelic treatment as a novel drug to treat MDD.
Prenatal Antidepressant SSRIs Linked to Offspring Brain Development Changes
A prospective cohort analysis of pregnant women in Rotterdam shows a potential link between the popular drug class and emotional regulation development trajectories.
What Goes Into a Valuable Dermoscopy
Ashfaq Marghoob, MD, discusses his recent workshop presentation on dermoscopies for skin cancer.
Mental Health Utility, Spending Significantly Increased Among Commercially Insured Adults
A study of 7 million-plus US adults shows telehealth visits for mental health conditions increased more than 10-fold during the COVID-19 pandemic.
7 Pharmacological Agents That Benefit Acute Bipolar Depression
A large systematic review assessing more than 60 drugs for bipolar depression shows only a handful were statistically signifcantly better than placebo per depressive symptom outcomes.
Sleep Interventions May Help Reduce Psychosis Risk in High-Risk Young Adults
A proof-of-concept trial shows a program that addresses sleep pressure, circadian rhythm and hyperarousal in adolescents and young adults receiving mental health care is promising.
Baclofen Benefits Cirrhosis, Alcohol-Associated Hepatitis Outcomes in AUD
A systematic review shows the muscle relaxant therapy is the lone intervention to benefit outcomes for the liver diseases among patients with alcohol use disorder, per randomized trials.
PTSD, Workplace Trauma Lower Among First-Year Residents During COVID-19
New cohort analysis shows residents entering medicine in 2020 were actually less likely to report symptoms of PTSD than their earlier peers.
Research Explores Link Between COVID-19 Vaccine Hesitancy and HBV, HPV Uptake
An analysis into correlation between COVID-19 vaccine uptake and that of more established vaccines showed research is lacking—yet troubling all the same.
Investigative Oral Targeted Budesonide Significantly Improves Berger Disease Over 9 Months
Phase 3 data show a significant clinical profile associated with durable reductions in IgA nephropathy biomarkers among patients treated with Nefecon.
Michael Liebowitz, MD: The Value of Fasedienol
The pioneer in social anxiety disorder discusses how the investigative nasal spay may alter the trajectory of patients' conditions.
Michael Liebowitz, MD: The History of Social Anxiety Disorder and Fasedienol
The pioneer in social anxiety disorder discusses his involvement in a promising, fast-acting nasal spray showing promising outcomes in late-stage trials.
Taha Qazi, MD: Evolving Bariatric Surgery Value in GI
Data support the benefit of bariatric surgery in patients at high risk of pancreatic ductal adenocarcinoma due to BMI and metabolic comorbidities.
Depression, Anxiety Symptoms Linked to Poor IBD Outcomes and Steroid Response
Instances of urgent IBD hospitalization, surgery, death or lack of response to steroid therapy are linked to symptoms of depression and anxiety.
Alcohol-Associated Hepatitis Hospitalizations Increased During COVID-19
Investigators find that while general hospitalizations decreased in 2020, hospitalizations due to alcohol-associated hepatitis increased by 16%.
Taha Qazi, MD: Addressing Smoking Cessation in the GI Office
Qazi reviews an analysis of an EHR-assisted smoking cessation module that could improve conversations between specialists and patients.
TERN-501 Significantly Reduces NASH Liver Fat Content in Phase 2 Trial
New 12-week data shows an investigative oral drug provided significant benefit in key outcomes associated with NASH disease relief.
Daily Sugar-Sweetened Drinks Linked to Increased Liver Cancer, Mortality in Older Women
An analysis of postmenopausal women shows a nearly two-fold increase in liver cancer incidence among those who consume at least 1 soft drink or fruit drink daily.
Nasal Spray Fasedienol Provides Rapid Social Anxiety Benefit in Phase 3 Trial
Vistagen reported significant improvement of physician- and patient-reported anxiety among trial participants who underwent an anxiety-inducing public speaking exercise.
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