Alcohol-Associated Hepatitis Hospitalizations Increased During COVID-19
Investigators find that while general hospitalizations decreased in 2020, hospitalizations due to alcohol-associated hepatitis increased by 16%.
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Taha Qazi, MD: Addressing Smoking Cessation in the GI Office
Qazi reviews an analysis of an EHR-assisted smoking cessation module that could improve conversations between specialists and patients.
TERN-501 Significantly Reduces NASH Liver Fat Content in Phase 2 Trial
New 12-week data shows an investigative oral drug provided significant benefit in key outcomes associated with NASH disease relief.
Daily Sugar-Sweetened Drinks Linked to Increased Liver Cancer, Mortality in Older Women
An analysis of postmenopausal women shows a nearly two-fold increase in liver cancer incidence among those who consume at least 1 soft drink or fruit drink daily.
Nasal Spray Fasedienol Provides Rapid Social Anxiety Benefit in Phase 3 Trial
Vistagen reported significant improvement of physician- and patient-reported anxiety among trial participants who underwent an anxiety-inducing public speaking exercise.
Taha Qazi, MD: Best Screening for Colorectal Cancer
While discussing a review of noninvasive options, the gastroenterologist addresses the growing interest in non-colonoscopy screening and surveillance methods.
Hepatitis C Treatment Initiation Low Among Younger, Female Medicaid Enrollees
Approximately 1 in 5 newly diagnosed patients are initiating direct acting antivirals within 6 months, according to Medicaid data review.
Fecal Microbiota Transplant Reduces UTI Risk in Recurrent C difficile
A Mayo Clinic study shows FMT may provide benefit for patients experiencing recurrent infections during their C difficile treatment.
FDA Approves Avacincaptad Pegol for Geographic Atrophy
The approval is the second granted to a geographic atrophy drug that targets the complement pathway.
Anita Clayton, MD: Zuranolone for Postpartum Depression
Clayton, a primary investigator in the drug's pivotal trials, discusses what the historic FDA approval means for managing PPD in women.
FDA Approves Zuranolone for Postpartum Depression
The approval marks the first indication for a postpartum depression drug—one that which has been touted for its rapid-acting effect and sustained benefits.
Taha Qazi, MD: Finding Upadacitinib's Role in Crohn's Disease
Qazi reviews the selective JAK1 inhibitor's benefit for patients who previously failed TNF inhibitor regimen.
People Cured of Hepatitis C Still Face Significant Mortality Risk
A multinational study shows people who achieve sustained virologic response still face a 3-fold greater risk or more of mortality due to liver disease or drug-related issues.
Hepatitis B Elimination Goal May Be Unrealistic for 2030
Global estimate prevalence data suggest the virus affects more than 3% of the population, with available treatment and vaccination strategies used too infrequently.
Lipid-Lowering Drug Target Linked to Increased IBD Risk
A protein targeted by some marketed lipid-lowering agents may increase risk of developing irritable bowel disease.
Cigarette Pack-Years Linked to Recurrent Colorectal Neoplasia in IBD Patients
The first known dose-effect relationship study between colorectal neoplasia and smoking in patients with IBD strengthens the importance of achieving cessation.
Apellis Reviewing Retinal Vasculitis Cases in Pegcetacoplan-Treated GA Patients
Reports of a half-dozen confirmed cases of the rare vision-threatening condition has spurred conversation around the first-in-class geographic atrophy drug.
Alcohol-Related Deaths Increasing Among US Women
New cross-sectional data show the sex gap in alcohol-related mortality has been narrowing since 1999, as women have become more susceptible to alcohol use and related diseases.
Patient Age, Antibiotics, and FMT Donor Influence Recurrent C. Difficile Resolution
New cohort analysis data provide more context into what factors influence the benefit of FMT in patients with recurrent CDI.
Patients with Crohn's Disease Report Low Calcium, Magnesium Intake
A study from China suggests calcium and magnesium malnutrition is associated with Crohn's disease inflammation and activity.
Julia Moore Vogel, PhD, MBA: How Do We Define Long Covid Patients?
Vogel reviews the struggles behind adequately diagnosing long Covid and quantifying its impact of disease at this time of clinical research.
US Maternal Hepatitis C Infections Increased 16-Fold Since 1998
Skyrocketing rates of HCV have aligned with the opioid epidemic—and evidence the need for universal pregnancy screenings.
Africa Challenged by Hepatitis B Mother-to-Child Transmissions
Though many countries established guidelines and strategies to eliminate the virus by 2030, the region is still behind on newborn virus management.
Julia Moore Vogel, PhD, MBA: Long Covid Care Lacks Urgency
Lungcast's July episode guest discusses how long Covid therapy development is still about 5 years away from the market.
High Parathyroid Hormone Levels Linked to NAFLD
A meta-analysis suggest the correlation between PTH and non-alcoholic fatty liver disease is significant enough for it to be biomarker for disease.
Alcohol-Associated Hepatitis Rapidly Increasing in the US
A retrospective analysis shows the highly deadly condition has increased 7-fold among US women in the last 2 decades.
Chronic Liver Disease Linked to Significant Risk of COVID-19 Pneumonia, Death
International data show conditions including cirrhosis and alcohol-associated liver disease significantly drive the likelihood of critical illness and death in COVID-19 patients.
Long COVID Research and Breakthroughs with Julia Moore Vogel, PhD, MBA
In the latest Lungcast, a nationally-leading researcher and long COVID patient discusses what's known and unknown about the chronic viral syndrome.
Amid Social and Political Strife, Medical Schools Seek a Modern Approach
Over 3 years, global health threats and national headlines have spurred medical schools to better address social and community-based determinants of health. What comes next?
CDC Experts Recommend Single-Visit Hepatitis C Antibody, RNA Testing
An update to guidances prioritizes practices that complete RNA testing on all HCV antibody reactive samples in one step, for the sake of complete test rates.