Blood Biomarkers, Aducanumab and Setting Precedent for Dementia Care Advances
Brent Forester, MD, MSc, discusses the confluence of biomarker and disease-targeting therapy in Alzheimer's, and the need to appropriately introduce these tools.
Nora D. Volkow, MD: Combating COVID-Era Issues in Substance Use Disorder
The director of NIDA discusses the unprecedented impact of the pandemic on overdose deaths—and how substance use disorder care may still reach greater capability when all is said and done.
The Challenges to Identifying Dementia, Alzheimer-Risk Patients
Dementia and Alzheimer's disease cases are anticipated to boom in coming decades. One expert stressed the need for improved screening and facilitation of care at the earliest stages and signs.
Guiding Appropriate Ketamine, Esketamine Use in Psychiatry
The lead author of treatment recommendations weighs in on their current use and future research.
How Evolving Psychiatric Definitions Set the Tone for Care
Amid significant psychotherapy innovation and consideration to broader aspects of mental illness definition, Jonathan Alpert, MD, PhD, emphasizes the need for improved clinical trial standards.
Adjunctive Cariprazine with Antidepressants Benefits Adult Major Depressive Disorder
New phase 3 data presented at APA 2022 support the agent as an adjunctive in older patients without benefit from monotherapy antidepressant medication.
How Mental Illness Definitions Are Still Being Uncovered and Refined
Montefiore psychiatry chair Jonathan Alpert, MD, PhD, discusses suggested updates to the DSM-5—with consideration to social determinants and patient-reported functioning.
The Pediatric Disaster Psychiatry Care Team
Linda Chokroverty, MD, discusses the significance of timing, communication and care coordination when children are affected by disasters or trauma.
Understanding Socially-Determined Mental Health and the Impact of COVID-19
APA president-elect Rebecca W. Brendel, MD, JD, discusses the need to prepare for a "twin mental health pandemic" while continuing to appropriately facilitate innovations in psychiatric care.
Zuranolone Benefits Major Depression, Postpartum Depression in Clinical Program
Anita Clayton, MD, reviews the available phase 2 and 3 clinical data for the novel, once-daily oral investigative drug.
The Need for Disaster Psychiatry Care
Linda Chokroverty, MD, discusses the role psychiatrists play in managing the mental health effects of disasters, and how children specifically may be impacted.
Eco-Anxiety and Contributing Mental Health Factors Among BIPOC
A pair of psychiatrists discuss how climate change and other social determinants of health are affecting the mental wellbeing of indigenous people.
Who Makes Up the Modern Dementia Care Team?
It takes even more than a village to provide the comprehensive care needed for aging, neurocognitive patients, says Rajesh R. Tampi, MD, MS.
Second-Generation Long-Acting Injectables Significantly Improve Long-Term Severe Schizophrenia Outcomes
A 6-year mirror analysis of risperidone, once-monthly paliperidone palmitate or once-monthly aripiprazole concludes suggesting the regimens may serve as an alternative to clozapine.
The Developing Dementia Definition, Treatment Field
Rajesh R. Tampi, MD, MS, discusses the evolved definition of dementia as a cognitive disorder, and how its spectrum of symptoms impact clinical development.
Dextromethorphan-Bupropion Significantly Improves Major Depression Symptoms in Phase 2 ASCEND
The first controlled trial of the combination therapy shows its benefit in 6-week depressive symptom improvement versus lone bupropion.
Appropriate C Difficile Testing May Vary by Hospital Setting, Physician
A South Korea in-hospital assessment found that approximately half of all ordered CDI tests did not meet recommendation standards.
Gut Microbiota Dybiosis May Be Linked to Rheumatic Disease
Developing research into the specific alterations of dysbiosis and diseases like arthritis suggest possibly novel pathways to therapy development.
Classifiers Could Identify Gastric Co-Infection Risks in Patients with COVID-19
New data suggest prediction of SARS-CoV-2 and bacterial co-infection or superinfection could be provided for hospitalized patients.
How Donation After Cardiac Death Heart Transplants Are Benefitting Care Centers
A Massachusetts General Hospital investigator explains how the innovative DCD practice addresses both waitlist issues and transplant center's capabilities.
How PREPARE Data, SMART Recommendations Alter Modern Asthma Strategy
Elliot Israel, MD, and Juan Carlos Cardet, MD, MPH, join Lungcast to discuss their latest research into addressing Black and Latinx asthma outcome disparities.
FDA Approves New Medtronic Stent for Coronary Artery Disease
The new drug-eluding stent can provide more flexible width size for patients with the potentially deadly disease.
FDA Decision on UCB's Bimekizumab for Plaque Psoriasis Delayed by CRL
Promising 2-year data for the IL-17 targeting biologic were recently presented at AAD 2022.
An Interview with a Medical Volunteer at the Ukraine-Poland Refugee Border
Massachusetts General Hospital surgery resident Selena S. Li, MD, discusses her overseas volunteer work caring for refugees escaping their home during the Russia invasion.
Sickle Cell Trait-Associated Dehydration Linked to Increased Risk of Death
Investigators observed a potential risk between Black individuals with baseline signs of dehydration, SCT and related mortality over 30 years.
FDA Extends PDUFA Timeline for MYFEMBREE Endometriosis Application
The daily oral combination therapy will be reconsidered for treating endometriosis pain this August.
Selena S. Li, MD: The US Heart Allocation System and Transplant Bridge Devices
The Massachusetts General Hospital investigator discusses how LVADs and mechanical circulatory supports have altered the national heart donor strategy.
How Viloxazine Extended-Release Capsules Alter Adult ADHD Care
Theresa R. Cerulli, MD, discusses the known clinical profile and evidential potential of the newest non-stimulant ADHD drug for adults.
The Unique Signs and Struggles of Adult ADHD
On the heels of the FDA approval of viloxazine extended-release capsules for adult ADHD, a neuropsychiatrist discusses the state of care and diagnosis among older patients.
Pass The Study: An Injected Stem Cell for Patients with Geographic Atrophy
In the first episode of this new game show, a team of ARVO 2022 investigators work to invent an innovative clinical trial.
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