Martin Weber, MD: The Role of B Cells and Antibodies in MS
Martin Weber, MD, spoke about the role that B cells and antibodies play in the treatment of multiple sclerosis.
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Siponimod Shown to Reduce Lesions, Slow Brain Volume Loss
The EXPAND trial results supported the potential neuroprotective effects of siponimod.
The Prevalence of Adult Onset ADHD, Reconsidered
Results showed that more than 80% of participants had their symptoms explained by other factors.
FDA Approves Golimumab for 2 New Indications
Previously approved for moderate-to-severe rheumatoid arthritis, golimumab received 2 new indications.
Opioid-Related Deaths Reduced by Legalized Cannabis
The drug’s legalization was found to be linked to a 6.5% decrease in opioid-related deaths in Colorado.
Do EMRs Provide Clinically Relevant Information?
As EMRs become more utilized and important, a study attempted to get a better understanding of their use.
FDA Advisory Committee Recommends Semaglutide
The FDA advisory committee voted 16-0 in favor semaglutide's approval.
Real-World COPD Trial Examines Triple-Combination Therapies
As COPD exacerbations continue to plague patients, the AIRWISE trial will examine LAMA/LABA/ICS combinations.
Determining the Optimal Length of Opioid Prescriptions
A study found that for general surgery, prescriptions were optimized at 4 to 9 days.
FDA Approves Senhance Robotic System
The system was approved to aid in minimally invasive surgeries.
FDA Advisory Committee Gives Nod to Rhopressa
The committee voted 10-0 in favor of efficacy and 9-1 in favor of safety.
FDA Approves New Formula for Pregabalin
Pfizer sought 3 indications for its formula, receiving approval for 2 of them, PHN and dDPN.
Trump Signs Executive Order on Health Care
The president requested regulations be developed to offer exemptions from the ACA regulations for health plans.
Merck Drops CETP Inhibitor Anacetrapib
After multiple roadblocks and a phase 3 trial, the company announced it will not file an NDA for the experimental drug.
The Impact of Cannabis on Public Health
The prohibition of cannabis has become a public health issue, according to Doctors for Cannabis Regulation.
Merck, KalVista Reach Agreement on Development of DME Drug
The therapy, KVD001, is scheduled to go into phase 2 studies later in 2017. The deal is reportedly worth $750M.
Is Gun Violence A Public Health Crisis?
Since 1968, deaths from gun violence have totaled more than 1.5 million. Is this public health concern now an epidemic?
FDA Approves Endurant Stent Graft System for AAA Patients
The approval was based on data that showed a technical success rate of 88.6% and a procedural success rate of 97.1%.
Single-Tablet HIV-1 Therapy Proves Efficacy, Safety to Standard of Care
The D/C/F/TAF combination tablet showed 2.5% virologic rebound and 94.9% virologic suppression in almost 800 patients.
Opioid-Related Death Risk Increased in Combination with Gabapentin
Concomitant use of gabapentin and opioids increased the risk of opioid-related death by almost 50%.
Raoul Concepcion, MD: Overlooked OAB Patients
Raoul Concepcion, MD, the director of the Comprehensive Prostate Center in Nashville, TN, talks about how a lack of specialized interest in overactive bladder can leave OAB patients to fall through the cracks.
Raoul Concepcion, MD: OAB Patients Presenting in Primary Care
Raoul Concepcion, MD, the director of the Comprehensive Prostate Center in Nashville, TN, discusses overactive bladder patients presenting to PCPs and the steps taken to care for them.
FDA Approves Zilretta for Osteoarthritis Knee Pain
The first-of-its-kind approval was based on data from a phase 3 randomized trial involving 484 patients around the world.
The Connected Clinician: Top Stories of the Week for October 6
Stay connected and up-to-date in health care news with the Connected Clinician top stories of the week for the week of October 6.
Adalimumab Tops List for Drug Spending, But Biosimilars Impact Impending
Adalimumab topped the list with AbbVie spending $13.6 billion on the drug in 2016, but the future remains in question as biosimilars' impact on the market looms in the distance.
Sanofi, Regeneron Offered New Trial in Alirocumab Dispute with Amgen
A federal judge has thrown out the March 2016 ruling in Amgen's favor, which blocked Sanofi/Regeneron's ability to take alirocumab to market.
Nobel Prize in Chemistry Awarded for Cyro-Electrion Microscopy
Awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson, the development has had a significant impact on medical research into infectious diseases.
FDA Issues Compounding Risk Alert for Vancomycin Amid Blinding Risk
Bilateral hemorrhagic occlusive retinal vasculitis (HORV)a potentially blinding adverse event, was associated with compounded triamcinolone, moxifloxacin, and vancomycin (TMV).
FDA Approves BOTOX Cosmetic for Third Indication
After previous indications in 2002 and 2013, the drug received its third indication for temporary improvement in the appearance of moderate to severe forehead lines associated with frontalis muscle activity
FDA Introduces Guidelines to Ease Approvals for Generics
The changes included new draft guidelines and improved clarity of the requirements.