CME Instructions

Cardiology Review® OnlineApril 2014
Volume 30
Issue 2

CME Reviews: Volume 30, No. 2

Release date: April 15, 2014

Expiration date: April 15, 2015

Media used: Internet-based

Estimated time to complete this CME activity: 1 hour

Statement of Need

Cardiovascular disease (CVD) is the leading cause of death in the United States. It is estimated that 83 million American adults have 1 or more forms of CVD. New agents, procedures, and interventions have improved patient outcomes, decreasing mortality and morbidity rates. However, as the population ages and as younger adults develop comorbidities due to unhealthy lifestyles, the patient population at risk for cardiovascular events is increasing.

Care for patients with CVD has become increasingly complex, and community-based cardiologists often struggle to stay up-to-date with the volume of new data. The overall goals of this publication are to provide timely and pertinent original research articles that review current guidelines, practices, and new developments in the field of cardiovascular medicine. The publication also emphasizes preventing CVD by modifying risk factors through such strategies as healthy eating, regular exercise, and avoidance of smoking.

Target Audience

The target audience for this activity is cardiologists.

April CME Learning Objectives

  1. Explain the effect that higher rates of imaging use at the hospital level have on downstream resource utilization and patient outcome.
  2. Quantify the cost-effectiveness of apixaban as an alternative for prevention of thromboembolic events in patients with atrial fibrillation.
  3. Assess the safety and efficacy of phentermine/topiramate ER and lorcaserin for chronic weight management.
  4. Explain the role of overweight and obesity independent of the presence or absence of metabolic syndrome in predicting risk of myocardial infarction and ischemic heart disease.
  5. Evaluate appropriate indications for renal artery stenting.
  6. Describe the factors associated with sleepiness and accident risk among long-distance highway drivers.

Financial Disclosure

As a sponsor accredited by the ACCME, it is the policy of Physicians’ Education Resource®, LLC (PER®), to require the disclosure of anyone who is in a position to control the content of an educational activity. All relevant financial relationships with any commercial interests and/or manufacturers must be disclosed to participants prior to the beginning of each CME activity. PER® has identified and resolved all conflicts of interest prior to the release of this activity.

Off-Label Disclosure and Disclaimer

This CME activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.

Sources of Funding

No educational grants from commercial interests were received.

Instructions for Receiving Credit

In order to receive a CME certificate for this activity, participants must

  • Read each review.
  • Take the pretest and record their answers online at
  • Take the posttest and record their answers online at A passing score of 70% or higher is required to obtain a CME certificate.
  • Complete the CME activity evaluation at Participants can immediately download their CME certificates upon successful passing of the posttest and completion of the CME activity evaluation.

Accreditation and Designation of Credit

Physicians’ Education Resource®, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physicians’ Education Resource®, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.



Debabrata Mukherjee, MD, MS, FACC

Chief, Cardiovascular Medicine

Clinical and Research Fellow

Vice Chairman, Department of Internal Medicine

Texas Tech University Health Sciences Center

El Paso, TX

Alison L. Bailey, MD

Assistant Professor of Medicine/Director

Cardiac Rehabilitation

University of Kentucky

Lexington, KY

Ragavendra R. Baliga, MD, MBA, FACP

Professor of Internal Medicine

The Ohio State University Medical Center

Columbus, OH

Zelia R. Budhan, MD

Charleston Area Medical Center Health Center

Charleston, WV

Harry E. Davis II, MD, FACP

Associate Professor of Medicine

Texas Tech University Health Science Center El Paso

El Paso, TX

Sucheta Gosavi, MD

Assistant Professor of Internal Medicine

Texas Tech University Health Science Center El Paso

El Paso, TX

Niki Katsiki, Msc, PhD, MD, FRSPH

Aristotle University of Thessaloniki

Thessaloniki, Greece

Kena Lanham, PharmD, BCPS

Cardiovascular Clinical Pharmacist

St. Vincent Indianapolis Hospital

Associate Professor of Pharmacy Practice

Butler University

Indianapolis, IN

Marian C. Limacher, MD, FACC, FAHA, FACP

Professor of Medicine

AHA Endowed Professor of Cardiovascular Research

Director, University of Florida

CTSI Training and Professional Development Program

University of Florida

Gainesville, FL

JoAnn E. Manson, MD, DrPH, FAHA, FACP

Chief, Division of Preventive Medicine

Brigham and Women’s Hospital Professor of Medicine

Michael and Lee Bell Professor Women’s Health

Harvard Medical School

Boston, MA

Dimitri P. Mikhailidis, BSc, MSc, MD, FRSPH, FCP, FFPM, FRCP, FRCPath

Academic Head, Clinical Biochemistry

Vascular Disease Prevention Clinics

Department of Surgery

University College London Medical School

London, UK

Aravinda Nanjundappa, MD

Professor of Surgery and Medicine

Robert C. Byrd Health Science Center

West Virginia University, Charleston Division

Charleston, WV

Mushabbar A. Syed, MD, FACC

Director of Cardiovascular Imaging

Rolf and Merian Gunner Professor of Medicine

(Cardiology), Radiology and Cell & Molecular Physiology

Stritch School of Medicine—Loyola University Chicago

Chicago, IL

Khaled M. Ziada, MD, FACC, FSCAI

Professor of Interventional Cardiology

Associate Professor of Medicine

Director of Cardiac Catheterization Laboratories

Director of Cardiovascular Interventional Fellowship Program

Gill Heart Institute

University of Kentucky

Lexington, KY

The following individuals have relevant financial relationship(s) with commercial interests to disclose:

Authors: Dimitri P. Mikhailidis, BSc, MSc, MD, FRSPH, FCP, FFPM, FRCP, FRCPath—Advisory Board Member, Member of Speakers’ Bureau, and Clinical Trial Investigator: Merck Sharp & Dohme Corp; Aravinda Nanjundappa, MD—Speaker’s Bureau: AstraZeneca and Janssen Pharmaceuticals, Inc; Alison L. Bailey, MD—Grants/Research Support: AstraZeneca

The following individuals have no relevant financial relationships with commercial interests to disclose:

Ragavendra R. Baliga, MD, MBA, FACP; Zelia R. Budhan, MD; Harry E. Davis II, MD, FACP; Sucheta Gosavi, MD; Niki Katsiki, Msc, PhD, MD, FRSPH; Kena Lanham, PharmD, BCPS; Marian C. Limacher, MD, FACC, FAHA, FACP; JoAnn E. Manson, MD, DrPH, FAHA, FACP; Mushabbar A. Syed, MD, FACC; Khaled M. Ziada, MD, FACC, FSCAI

Planner, reviewer, and editor-in-chief: Debabrata Mukherjee, MD, MS, FACC

PER planners and staff: Megan O’Connell; Emily Valko

Cardiology Review staff: Bea Riemschneider; Jackie Syrop

Provider Contact Information:

Physicians’ Education Resource®, LLC

666 Plainsboro Road, Suite 356

Plainsboro, NJ 08536

Toll Free: 888-949-0045

Local: 609-378-3701

Fax: 609-257-0705

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