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This Year In Medicine 2025

Opinion|Videos|May 30, 2024

Mavacamten in oHCM: Navigating the REMS Program for Safe, Optimal Outcomes

Author(s)Anjali Tiku Owens, MD

Anjali Tiku Owens, MD, examines mavacamten, the pioneering cardio myosin inhibitor (CMI) approved for the treatment of obstructive hypertrophic cardiomyopathy (oHCM), which is exclusively accessible through the restricted Risk Evaluation and Mitigation Strategy (REMS) program; the KOL delves into the objectives of this program and how it strives to enhance medication safety and optimize patient outcomes.

Episodes in this series

Video 1 - "Novel Cardio Myosin Inhibitors Targeting Obstructive Hypertrophic Cardiomyopathy's Root Cause "

EP. 1 Novel Cardiac Myosin Inhibitors Targeting Obstructive Hypertrophic Cardiomyopathy's Root Cause

Video 2 - "Lessons from EXPLORER-HCM: Unveiling CMIs' Potential in oHCM Treatment "

EP. 2 Lessons from EXPLORER-HCM: Unveiling CMIs' Potential in oHCM Treatment

Video 3 - "Aligning With 2023 ESC Guidelines in oHCM Treatment"

EP. 3 Aligning With 2023 ESC Guidelines in oHCM Treatment

Video 4 - "Mavacamten in oHCM: Navigating the REMS Program for Safe, Optimal Outcomes "

EP. 4 Mavacamten in oHCM: Navigating the REMS Program for Safe, Optimal Outcomes

Video 5 - "Real-World Insights: Navigating Cardiac Myosin inhibitors in Practice" - Featuring 1 KOL

EP. 5 Real-World Insights: Navigating Cardiac Myosin inhibitors in Practice

Mavacamten is the first approved CMI for oHCM and is only available through the restricted Risk Evaluation and Mitigation Strategy (REMS) program. What is the purpose of this program, and how does it aim to improve medication safety and patient outcomes?
How does your institution/clinic handle the execution of the REMS program for mavacamen, how do you get certified, what are the institutional protocols?

What is needed from the patient? REMS program patient

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