
New data support the “two-hit” hypothesis: early allergic sensitization plus respiratory infections may impair lung function into adulthood, up to age 25 years.

Chelsie Derman is an associate editor for HCPLive who covers allergy and psychiatry. She joined MJH Life Sciences in September 2023 after graduating from The College of New Jersey with a bachelor’s degree in journalism and professional writing. In her free time, she enjoys creative writing and reading.
She can be reached at [email protected].

New data support the “two-hit” hypothesis: early allergic sensitization plus respiratory infections may impair lung function into adulthood, up to age 25 years.


Lyra Therapeutics announced LYR-210 met primary and secondary endpoints in phase 3 ENLIGHTEN 2, improving CRS symptoms and showing strong safety.

Systematic review of 34 randomized trials finds EMDR most effective, though civilians were more likely than veterans to lose their PTSD diagnosis after treatment.

Despite controversy, new data show that even high-risk pediatric patients may benefit from a gradual, supervised reintroduction of milk and egg.

Katherine Dahlsgaard, PhD, and Megan Lewis, MSN, discuss how proximity challenges can reduce medically unnecessary avoidance for patients with food allergy anxiety.

Despite shifting guidelines and growing awareness, food allergies continue to rise, and experts point to multiple possible culprits.

Female sex, CRSsNP, prior sinus surgery, and allergies are linked to worse postnasal discharge in chronic rhinosinusitis, a recent study found.

All surgical options for rhinitis, including turbinate and posterior nasal nerve procedures, significantly reduce congestion, rhinorrhea, and other symptoms.

Study suggests age 2 may be optimal for hen’s egg oral food challenge in FPIES. Early OFCs linked to higher risk of positive results in Turkish pediatric cohort.

New clinical guidelines offer 11 key actions for managing chronic rhinosinusitis, guiding surgery decisions, and improving patient care.

Despite 2020 guidelines discouraging first-generation antihistamines, ED diphenhydramine use for anaphylaxis and urticaria remained unchanged since 2019.

A recent study validated an online tool’s ability to accurately predict peanut allergy; the basophil activation test was the top performer, especially when paired with Ara h 2-sIgE.

A new study identifies GDNF, IL-18R1, and IL-15RA as key biomarkers in seasonal allergic rhinitis, linked to symptom severity and immune pathways.

A new study found ocular allergy affects 49.3% of students aged 11–18 years in Trinidad and Tobago—greater than in the US, Sweden, Brazil, and Uganda.

Only 50.3% of physicians consistently manage drug hypersensitivity. Study urges mandatory training, better protocols to improve patient safety.

AC-201 at 25, 50, and 100 mg doses show promising phase 2 results, significantly reducing psoriasis severity.

High cow’s milk- and casein-specific IgE levels were key risk factors for reactions, including anaphylaxis, during low-dose oral food challenges in children.

The allergy medications of cetirizine or levocetirizine have led to pruritus in some patients who stopped using the medications after using them daily for a few months or years.

Miranti shared 2025 acne and rosacea trends, as well as an overlapping treatment option for patients with both conditions, at New Wave Dermatology.

At 2025 New Wave Dermatology, Zirwas highlights the most useful dermatology studies from the past 2 years, covering AD misdiagnosis, alopecia, contact dermatitis, and more.


A study reveals CoMiSS effectively monitors symptom improvement in infants with cow's milk allergy during elimination diets, guiding dietary adjustments.

FDA accepts BioCryst’s NDA for berotralstat oral granules in kids with HAE; priority review granted. Approval could bring first oral prophylactic for kids aged <12 years.

A study reveals that two-thirds of children with high-risk cow's milk allergies tolerate baked milk, suggesting potential for early allergy management.

New findings reveal that timing of antihypertensive medication—bedtime vs. morning—shows no significant impact on health outcomes for frail older adults.

A study shows that many children with pollen allergies face ongoing symptoms into adulthood, highlighting the need for better management.

Advanced biological aging significantly associated with the dementia risk, a new study found.

A study reveals key risk factors for anaphylaxis from non-severe drug hypersensitivity, emphasizing the need for caution in drug administration.

New research reveals older adults face higher anaphylaxis risks from medications and IV contrast, often presenting with severe symptoms and outcomes.