The HCPLive nephrology page is a resource for medical news and expert insights on kidney disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments in nephrology, and more.
Study Confirms Efficacy of Terlipressin for Type 1 Hepatorenal Syndrome
Use of the vasoconstrictor was associated with increased risk for death due to respiratory disorders.
Ibuprofen Use in Children Linked to Hospital-Acquired Kidney Injury
Risk was greater in children requiring intensive care, those with chronic kidney disease, and older patients.
Kidney Transplant Linked to Lower Mortality Risk in Sickle Cell Patients
Although overall decrease in mortality was similar to the control group, sickle cell populations were still less likely to receive a kidney transplant.
American Kidney Fund Launches Awareness Campaign for Primary Hyperolaxuria
Individuals with PH are often undiagnosed or misdiagnosed; therefore, the exact prevalence of the disorder is unclear.
Anemia Prevalence Greater in Mexican Patients on Hemodialyis
Prevalence of anemia in patients with chronic kidney disease on hemodialysis found higher in Mexico than studied populations, with similar contributing factors.
Kidney Transplantation Needs Improvement for ESKD Patients
Investigators conclude improvements in kidney transplantation may require significant interventions.
Microalbuminuria Is Higher in Patients With Uncontrolled Diabetes
The new study underscores the importance of annual urine analysis to catch signs of diabetic nephropathy.
Fabry Disease Gene Therapy AVR-RD-01 Completely Reduces Toxic Kidney Substrate
New WORLDSymposium findings show a treated patient had 100% reduction in the accumulating fatty substrate associated with the burdensome rare disease after 1 year.
Corticosteroid Withdrawal Post-Kidney Transplant Linked to Long-Term Safety
The adverse effects of corticosteroids have underscored a need to eliminate the drug from treatment regimens.
FDA Approves Voclosporin for Lupus Nephritis
The treatment represents the first ever oral therapy approved by the FDA for lupus nephritis.
Risk for Hospital-Acquired AKI and C diff with Antimicrobials
Using piperacillin/tazobactam increases the risk for acute kidney injury, and this risk can be exacerbated by concurrent vancomycin.
FDA Grants Priority Review for Dapagliflozin
If approved, the treatment would be the first SGLT2 inhibitor for patients with chronic kidney disease.
Stopping RAS Inhibition Therapy Increases Risk of Cardiovascular Events
Patients who continue RAS therapy had a lower risk of kidney replacement therapy.
Canagliflozin Improves Anemia in Diabetics with Renal Impairment
The SGLT2 inhibitor demonstrated possible erythropoietic effects in type 2 diabetes patients.
FDA Approves Generic Glucagon Injection for Hypoglycemia
The first approved generic product for injection glucagon is also indicated for diagnostic use, when appropriate.
FDA Extends PDUFA Date for Roxadustat
FibroGen will submit additional data for the New Drug Application.
New Study Promotes Kidney Transplantation for HCV Positive Donors
There was not a statistically significant difference in eGFR between kidney recipients of HCV positive and negative donors.
Gerald Shulman, MD, PhD: The Future of Diabetes Treatments
Dr. Gerald Shulman discusses how diabetes can eventually be reversed.
Gerald Shulman, MD, PhD: Solving the Mystery of Insulin Resistance
By addressing insulin resistance, researchers believe they can reduce the comorbidities associated with type 2 diabetes.
Francesco Giorgino, MD, PhD: Optimizing Diabetes Treatment with SGLT2 Inhibitors
Dr. Giorgino discusses how combining SGLT2 Inhibitors and GLP-1RA could be combined for treating type 2 diabetes.
George Bakris: The Future of Finerenone as a Diabetes Treatment
More studies are planned testing the impact of finerenone.
George Bakris, MD: Finerenone Showing Promise Treating Type 2 Diabetes
Finerenone could be another option to SGLT2 inhibitors for this patient population.
FDA Approves First Drug for Primary Hyperoxaluria Type 1
The indication comes from collaborative work among experts and community leaders coordinated by the Oxalosis & Hyperoxaluria Foundation and the Kidney Health Initiative.
DAA Regimen Decreases HCV Risk in Kidney Transplant Recipients
A week-long treatment program prevented HCV transmission in 88% of cases.
Obinutuzumab Provides Two-Year Benefits for Lupus Nephritis
The monoclonal antibody has built on its 18-month portfolio with sustained renal benefits for the at-need patient group.
Voxelotor Tolerable, Safe for Sickle Cell Patients with Hepatic, Renal Disease
New phase 1 data show the first-in-class oral therapy is not affected by the burden on metabolism via hepatic or renal disease.
Investigators Explore Role of Sickle Cell in Risk of Acute Kidney Injuries
In data presented during Kidney Week, researchers find the risk of developed an acute kidney injury increased in both sickle cell trail and sickle cell disease patients.
C. Diff Guidelines Effective in Predicting Severity for Kidney Disease Patients
The absolute SCr criterion correlated better with all-cause mortality than the relative increase in serum creatinine.
Chronic Kidney Disease Increases Hospital Stays for Pediatric Patients
Length of stay, cost, and the mortality rate all increase among patients with chronic kidney disease compared to patients who do not suffer from CKD.
Alan S. Kliger, MD: Fighting the Flu and COVID-19
Dr. Kliger discusses how nephrologists can safely treat patients this winter.
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