The HCPLive Rheumatology condition center page is a comprehensive resource for clinical news and insights on rheumatologic disease. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for arthritis, gout, nr-AxSpA, and more.
June 3rd 2023
After 12 weeks of treatment, the median sUA levels of patients with gout were reduced from 8.6 mg/dL to 3.6 mg/dL in the AR882 75 mg cohort and 5.0 mg/dL in the AR882 50 mg group.
Match Day's Hidden Crisis: Pediatric Rheumatology Struggling to Meet PaceMarch 17th 2023
Often overlooked and underfunded, as well as being underpaid compared to internal medicine, it is difficult to convince prospective medical students, many of whom already have substantial debt, to choose a career in pediatric rheumatology.
Is PJP Prophylaxis Indicated in Patients With Giant Cell Arteritis or Polymyalgia Rheumatica?March 12th 2023
Results of a recent study showed that the risk of pneumocystis jiroveci pneumonia (PJP) is low in patients with giant cell arteritis (GCA) and polymyalgia rheumatica (PMR), therefore discouraging the routine prescribing of PJP prophylaxis for this patient population.
Tumor Necrosis Factor Inhibitors Safely, Effectively Treat Patients With Juvenile Idiopathic ArthritisMarch 1st 2023
Results of a recent review showed that adalimumab, etanercept, golimumab, and infliximab are effective and well-tolerated treatments options for patients with juvenile idiopathic arthritis.
Better Self-Efficacy Linked to Better Health-Related Quality of Life in Patients With SLEFebruary 27th 2023
Multivariable models indicated that improvements in the physical component score and mental component score could be predicted by better self-efficacy scores in patients with systemic lupus erythematosus.
Serological Screening Recommended for Patients With JIA and a Family History of Thyroid DiseaseFebruary 27th 2023
Patients with juvenile idiopathic arthritis were at a greater risk of developing autoimmune thyroid disease if they were female, reported ANA and/or RF positivity, and a family history of thyroid disease.
Multidisciplinary Lifestyle Program Decreased Disease Activity in Patients With Rheumatoid ArthritisFebruary 3rd 2023
“Reversing and preventing adverse lifestyle factors could potentially reduce the incidence and burden of rheumatoid arthritis, as well as alleviate its comorbidities,” investigators hypothesized.
Aerobic Telerehabilitation Program did not Significantly Improve Disease Activity in Women With FibromyalgiaFebruary 2nd 2023
Investigators measured pain intensity, the primary outcome, as well as physical function, isometric strength, quality of life, and fibromyalgia impact at baseline and the 6-month mark.
Patients With Inflammatory Arthritis Feel Positive Toward Most Vaccinations
General practitioners and rheumatologists were viewed as sources of information that led to positive views toward vaccinations, while internet chatrooms, social media, and mainstream media were seen as sources of information that led to negative views.
Targeting the MK2 Pathway Reduces Tachyphylaxis Related to Rheumatoid Arthritis TherapyJanuary 24th 2023
P38 mitogen-activated protein kinase (p38 MAPK) inhibitors have been a focal point for inflammatory diseases but the lack of efficacy in treating rheumatoid arthritis led to examination of the MK2 pathway.
Low- vs High-Dose Exercise Programs Yielded Similar Benefits in Patients with Knee OsteoarthritisJanuary 23rd 2023
The multicenter superiority trial evaluated patients with diagnosed knee osteoarthritis and a history of pain and decreased knee function using patient-tailored exercise programs.
Greater Pre-Existing Radiographic Damage in Psoriatic Arthritis May Reduce Chance of Full Inhibition With SecukinumabJanuary 23rd 2023
Secukinumab therapy was associated with inhibition of joint tenderness and swelling, but high baseline radiographic damage was associated with reduced likelihood of full inhibition.
Studies Focused on Benefits of Acupuncture, Electroacupuncture Increasing in Number in FibromyalgiaJanuary 21st 2023
The findings visualized the increased amount of research regarding acupuncture for fibromyalgia treatment, which may eventually boost efficacy, reduce cost, and promte future development in the field.
Vitamin D Deficiency Common Among Patients with Systemic Lupus ErythematosusJanuary 20th 2023
The 2-phase study analyzed the association of plasma vitamin D levels with clinical phenotype, serology, and disease variables in a large cohort of patients with systemic lupus erythematosus living in India.
Physical Inactivity Levels Associated with Higher Pain Scores, Depression Rates in Patients with Rheumatoid ArthritisJanuary 19th 2023
“Despite the multiple benefits offered by physical activity (PA), the proportion of older adults meeting PA guidelines is between 27% to 44%," investigators explained.
Quantifying the Association Between Anxiety and Depressive Features and High Disease Activity Scores in SLEJanuary 19th 2023
Anxiety and depression can limit engagement with healthcare or treatment leading to later diagnosis, poor treatment adherence, and poor disease control with associated negative sequelae.
Yoga, Cognitive Behavioral Therapy Improved Patient-Reported Outcomes in Fibromyalgia, IBSJanuary 18th 2023
Improved patient-reported outcomes were observed in patients who used mind-body interventions, such as cognitive behavioral therapy and yoga, and were effective for managing IBS and fibromyalgia.