A 59-year-old man presented to clinic with concerns that his ezetimibe prescription was causing an itchy rash. The rash first appeared on his hand 1 year ago and now it involves his arm, as well. The man's past medical history is significant for coronary artery disease, hypertension, hyperlipidemia, and hypothyroidism. He has tried a topical antifungal agent and oral fluconazole to no avail.
While tamoxifen and raloxifene reduce the incidence of invasive breast cancer and fractures, they also increase the risk of deep venous thrombosis, cataracts, and uterine cancer.
Because e-cigarettes are marketed as a "safer alternative to tobacco smoking," concerns have surfaced regarding the potential for long-term health consequences that stem from inhaling vapor containing nicotine, propylene glycol, and by-products, as well as exposing bystanders to the substance second-hand.
Among patients with peripheral artery disease and intermittent claudication, a daily dose of 10 mg ramipril can improve pain-free treadmill walking times, which are associated with a significant increase in physical functioning.