Frank J. Domino, MD

Articles by Frank J. Domino, MD

Using a questionnaire based survey of children from Scandinavia, these authors correlated asthma, eczema, and rhino-conjunctivitis, and found lower rates of these outcomes in those who hand washed as opposed to those who machine washed their dishes.

There is consistent observational data that identifies concomitant use of proton pump inhibitors for gastroesophageal reflux disease and clopidogrel following acute coronary syndrome increases the risk of recurrent cardiovascular events. While a variety of theories exist (lower pH alters absorption, etc.), no clear factor has been identified.

The IBIS-I randomized control trial included women of ages 35-70 from 37 health centers in eight countries from April, 1992, until March, 2001 that were deemed to be at increased risk of developing breast cancer (by virtue of family history of breast cancer or abnormal benign breast disease), and randomized to treatment with oral tamoxifen or placebo for 5 years.

This study was a randomized, controlled trial of 240 adults with metabolic syndrome who were assigned to follow either the single-component dietary recommendation of increased fiber consumption (≥30g/d), or the multi-component American Heart Association (AHA) dietary guidelines. The primary outcome measure was weight loss at 12 months.

Patients with high body mass indexes and obesity are at greater risk for developing obstructive sleep apnea. This meta-analysis looked to determine if the use of Continuous Positive Airway Pressure for sleep apnea would result in weight loss or weight gain.

Crops raised in a method that meets the organic standard contain more antioxidants than traditionally grown crops. Nevertheless, it remains unproven whether diets with higher antioxidant concentrations provide improved health outcomes.