Paul Erne, MD2: From the 1AMIS Plus Data Center, Institute of Social & Preventive Medicine, University of Zurich, 2department of cardiology, Canton Hospital


Sex-related differences in treatment and outcome in patients with ACS

The AMIS (Acute Myocardial Infarction in Switzerland) Plus prospective cohort study compared treatment and in-hospital outcomes between men and women with acute coronary syndrome (N = 26,452) admitted to Swiss hospitals between 1997 and 2007. The study reached several important conclusions: women had different baseline characteristics than men at admission, were treated with different drug regimens, and were significantly less likely to undergo percutaneous coronary intervention. After adjusting for these differences, researchers found no significant difference in the rates of in-hospital mortality between men and women, except for women aged 51 to 60 years, who were more likely to die in-hospital.

The Copenhagen City Heart Study, Bispebjerg University Hospital, University of Copenhage


Nonfasting triglycerides and ischemic heart disease in men and women

Triglyceride levels are usually measured after the patient has fasted, and then exclude remnant lipoproteins. Except for the first few hours of the morning, individuals are usually in a nonfasting state for most of the day. We investigated whether nonfasting triglyceride levels predicted the risk of myocardial infarction (MI), ischemic heart disease, and death in the general population. Results showed that increased nonfasting triglyceride levels were associated with an increased risk of MI, ischemic heart disease, and death.

Brahmajee K. Nallamothu, MD, MPH, is assistant professor of internal medicine, Cardiovascular Center, University of Michigan, Ann Arbor, MI.


Early invasive or selective invasive strategies for ACS patients

Treatment of stable patients with acute coronary syndrome (ACS) is controversial. Until recently, large randomized clinical trials had indicated that an "early" invasive strategy with routine cardiac catheterization reduced the likelihood of recurrent cardiovascular events when compared with a more "selective" approach, in which stable patients were referred to cardiac catheterization based on high-risk features on noninvasive stress imaging or because of a failure in initial medical therapy.

Marco Meglio


COVID-19 and the Brain: Understanding the Neurological Effects of the Virus as the Pandemic Evolves

Almost 4 years since the beginning of the pandemic, continuous research efforts have begun to paint a better picture of the impact the virus has on the brain and the central nervous system.

RosaMaria Marfisi, MS


The prognostic role of metabolic syndrome after myocardial infarction

We evaluated the prognostic role of metabolic syndrome after myocardial infarction and found that metabolic syndrome correlated with an increased risk of cardiovascular events and death. The risk of developing diabetes decreased with weight loss in patients with metabolic syndrome. These results indicate that a more aggressive approach to the treatment of patients with metabolic syndrome, particularly with regard to changes in lifestyle, would be beneficial.

Abe W. Friedman, MD


Intermittent inotropic therapy: A clinician's opinion

Can any physician consider using intermittent inotropic therapy in patients with congestive heart failure?

Roxanne Williams-Truax, RN, BSN, OCN


The Nurse's Role in Recruitment and Retention of Clinical Trial Participants

Recruiting patients to participate in clinical trials is a challenging and time-consuming endeavor, especially when it comes to cancer clinical trials.

Timothy Hoff, PhD


AJMC Study Looks at the Shaky Foundation of the Patient-centered Medical Home

The patient-centered medical home has been proposed as a solution to the challenges facing primary care, but there are several concerns over whether this approach is feasible.

Michael F. Myers, MD


Lessons Learned from My Doctor-Patients

A doctor writes on his experiences in treating colleagues in his psychiatry practice, and the humility he's gained from it.

Dawn Laney, MS, CGC, CCRC, Assistant Professor


Case-Based Peer Perspectives in Fabry Disease

Dawn Laney, MS, CGC, CCRC, Assistant Professor and Director, Emory Genetic Clinical Trials Center, talks misdiagnosis in Fabry disease through a case study.

Michael J. Gaunt, PharmD


Keeping Patients Safe from Methadone Overdose: A Pharmacist's Perspective

Confusion between methadone and other medications with lookalike names can cause life-threatening errors.

Oncology & Biotech News Editors


Chemotherapy Foundation Symposium Overview

This year's Chemotherapy FoundationSymposium, entitled

Mark A. Becker, MD


Provide Your Patients with an Online Resource You can Both Trust...Your Own!

Patients are going online for health information but would prefer to get it from you. Are you there to help them?

Atsushi Hozawa, MD, PhD


White-coat hypertension and progression to home hypertension

Our study aimed to clarify whether white-coat hypertension represents a transient state in the development of hypertension outside medical settings. We followed up 128 subjects with white-coat hypertension and compared their risk of progression to home hypertension with that of 649 sustained normotensive subjects. After 8 years of follow-up, subjects with white-coat hypertension had an approximately 3-fold higher risk of eventually manifesting home hypertension. We concluded that patients with white-coat hypertension should be carefully monitored.

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