Kris Kowdley, MD, FACP, FACG, AGAF, FAASLD

Articles by Kris Kowdley, MD, FACP, FACG, AGAF, FAASLD

Volixibat's Safety Profile Explained for PSC, With Kris Kowdley

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD

May 14th 2026

GI and liver safety signals for clinicians to know from the VISTAS evaluating volixibat in PSC-associated pruritus.

Volixibat Shows Rapid Itch Relief in PSC in Phase 2b VISTAS Trial, With Kris Kowdley, MD

Volixibat Shows Rapid Itch Relief in PSC in Phase 2b VISTAS, With Kris Kowdley, MD

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD

May 13th 2026

Kowdley explains phase 2b VISTAS data suggesting volixibat rapidly reduced PSC-associated pruritus in adults with limited treatment options.

Liver Lineup: Innovations in Cholestatic Disease Management, With Kris Kowdley, MD

ByNancy Reau, MD,Kris Kowdley, MD, FACP, FACG, AGAF, FAASLD

September 18th 2025

Kowdley joins Liver Lineup to discuss evolving approaches in cholestatic liver disease and recent progress in PBC.

Unmet Needs in the Treatment of PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

August 3rd 2023

Experts in hepatology review the unmet needs in primary biliary cholangitis, commenting on liver transplant, ethnic disparities, management of pruritis, as well as other symptoms.

Emerging Treatment Options in PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

August 3rd 2023

Sonal Kumar, MD, MPH, and David Victor III, MD, provide an overview of the emerging treatments in the primary biliary cholangitis landscape, highlighting PPAR agonists and combination OCA and bezafibrate.

Triple Therapy in PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

July 27th 2023

Hepatology experts discuss the use of triple therapy in the management of PBC as the wave of the future.

Switching Treatment in PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

July 27th 2023

Experts in hepatology comment on how long they keep a patient with PBC on first-line treatment before deciding to switch to another therapy.

Real-World Data on OCA in PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

July 20th 2023

Hepatology experts review the real-world studies of obeticholic acid for management of PBC, highlighting data that show obeticholic acid could improve clinical outcomes in PBC.

Managing OCA-Induced Pruritis in PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

July 20th 2023

Sonal Kumar, MD, MPH; and Edward Mena, MD, share their approach to managing pruritis brought on by OCA in patients with PBC.

Safety Considerations With OCA in PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

July 13th 2023

Experts in hepatology discuss safety considerations for use of OCA in patients with cirrhosis and decompensated cirrhosis.

Use of Obeticholic Acid (OCA) in PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,David Victor III, MD

July 13th 2023

Steven Flamm, MD, FAASLD, FACG, reviews the option of using OCA to manage PBC in patients who cannot tolerate UDCA.

Current Treatments for PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

July 6th 2023

Experts reviews the current treatment landscape for management of PBC, highlighting ursodeoxycholic acid (UDCA) and obeticholic acid (OCA), as well as liver transplant.

Treatment Selection for Patients With PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

July 6th 2023

Drs Kris Kowdley, Steven Flamm, Sonal Kumar, Edward Mena, and David Victor discuss their approach to initiating treatment of PBC as well as managing this chronic condition.

Guidelines and Risk Stratification of PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

June 29th 2023

A panel of experts reviews the tools available to risk stratify patients with PBC, highlighting the GLOBE score and liver elastography.

Care Management in PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

June 29th 2023

Kris Kowdley, MD, FACP, FACG, AGAF, FAASLD, reviews the changes in the screening and diagnosis of primary biliary cholangitis in the recently published CDLF guidelines, as well as when a primary care physician should refer a patient to a specialist to assess disease presence.

Diagnosis of PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

June 22nd 2023

Experts in hepatology share their approach to diagnosing primary biliary cholangitis and discuss the use of liver biopsies in diagnosis.

Impact of PBC on Quality of Life

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

June 22nd 2023

Steven Flamm, MD, FAASLD, FACG, reviews the disease burden of primary biliary cholangitis on the patient and their family. He also comments on the impact PBC has on a patient’s mental health.

Disease Progression of PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

June 15th 2023

Experts in hepatology discuss disease progression of PBC and the long-term complications patients may experience.

Triggers and Risk Factors of PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

June 15th 2023

David Victor III, MD, comments on the risk factors for PBC and the importance of educating the patient about the disease.

Classification of PBC

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

June 8th 2023

Edward Mena, MD, reviews the classification and diagnosis of PBC considering the change from the term “cirrhosis” to “cholangitis.”

Overview of Primary Biliary Cholangitis (PBC)

ByKris Kowdley, MD, FACP, FACG, AGAF, FAASLD,Steven Flamm, MD, FAASLD, FACG,Sonal Kumar, MD, MPH,Edward Mena, MD,David Victor III, MD

June 8th 2023

Sonal Kumar, MD, MPH, provides an overview of primary biliary cholangitis (PBC) and its recent increase in prevalence, as well as common signs and symptoms.