Anaphylaxis

Shaker shares how allergist-immunologists can use brief CBT, motivational interviewing, and risk reframing to shift patients’ fear of their food allergies into confidence.

With the FDA acceptance of the NDA, the agency has assigned a PDUFA target action date of January 31, 2026, and may require an Advisory Committee meeting for approval.

UK study finds atopic conditions, especially anaphylaxis, significantly raise the risk of anxiety, depression, OCD, and other mental illnesses in primary care patients.

Asthma and peanuts were identified as key risk factors for grade 4 anaphylaxis in a retrospective study, highlighting the need for tailored prevention.

Despite controversy, new data show that even high-risk pediatric patients may benefit from a gradual, supervised reintroduction of milk and egg.

Katherine Dahlsgaard, PhD, and Megan Lewis, MSN, discuss how proximity challenges can reduce medically unnecessary avoidance for patients with food allergy anxiety.

Despite shifting guidelines and growing awareness, food allergies continue to rise, and experts point to multiple possible culprits.

Moderate-severe asthma, anaphylaxis, and allergic rhinitis risk are all higher in children with atopic dermatitis and food allergy.

Study suggests age 2 may be optimal for hen’s egg oral food challenge in FPIES. Early OFCs linked to higher risk of positive results in Turkish pediatric cohort.

Despite 2020 guidelines discouraging first-generation antihistamines, ED diphenhydramine use for anaphylaxis and urticaria remained unchanged since 2019.

High cow’s milk- and casein-specific IgE levels were key risk factors for reactions, including anaphylaxis, during low-dose oral food challenges in children.

A study reveals CoMiSS effectively monitors symptom improvement in infants with cow's milk allergy during elimination diets, guiding dietary adjustments.

A study reveals that two-thirds of children with high-risk cow's milk allergies tolerate baked milk, suggesting potential for early allergy management.

These data compare the characteristics and trends of anaphylaxis caused by goat and sheep’s milk allergies with those of cow’s milk and peanut allergy.

A study reveals key risk factors for anaphylaxis from non-severe drug hypersensitivity, emphasizing the need for caution in drug administration.

New research reveals older adults face higher anaphylaxis risks from medications and IV contrast, often presenting with severe symptoms and outcomes.

A recent study reveals that anaphylaxis rates remain stable during the COVID-19 pandemic, despite reduced emergency visits.

Patients with HαT showed a 13% prevalence of drug-induced anaphylaxis, with greater risk tied to antibiotic- and monoclonal antibody-triggered reactions.

Tryptase, although identified as the most reliable anaphylaxis biomarker in a recent systematic review, only had a 49% sensitivity.

A survey reported that among 98.3% of respondents prescribed an epinephrine autoinjector for food allergies, 75.1% expressed concern about obtaining it.

In a recent study, a diagnostic protocol of 1:10 intradermal tests and subcutaneous provocation showed high accuracy for diagnosing immediate-type anesthetic allergy in children.

In children with septic shock, norepinephrine as the first vasoactive agent was linked to lower 30-day mortality than epinephrine, with no renal outcome difference.

Aquestive’s Anaphylm study showed positive pharmacokinetic results in children and adolescents, supporting its FDA submission.

A study found omalizumab enables faster, safer desensitization in children with food allergies, improving oral immunotherapy outcomes and reducing reactions.