Anaphylaxis

Research links Treg activity, B-cell suppression, and gastrointestinal immune regulation to the success and failure of peanut oral immunotherapy.

Study highlights risk factors and diagnostic accuracy for immediate-type local anesthetic allergy in children.

Study reveals 7 communication strategies clinicians can use to convey allergy risk and guide adrenaline auto-injector decisions in pediatric consultations.

MGH investigators confirmed the reliability of the Drug Allergy History Tool (DAHT), which outperformed EHR documentation in completeness.

Four allergens not on the FDA or EFSA food allergy list show high frequency in a recent study. Anaphylaxis induced by goat or sheep milk led to 2 deaths.

A discrete choice experiment revealed food allergy treatment preferences among adolescents, with efficacy ranking as the most important attribute.

Multicenter study finds most children with anaphylaxis can be safely discharged within 2 hours, with 4 hours for those with cardiovascular involvement.

A new advisory highlights cephalexin’s efficacy and low cross-reactivity risk, supporting its safe use in patients with penicillin allergy.

New research confirms that adrenaline is safe and effective for anaphylaxis, debunking myths.

In this large study, oral berotralstat resulted in early and sustained reductions in HAE attack rates, offering a promising long-term prophylaxis option.

In a study of children with food allergy and atopic dermatitis, longer dupilumab use was associated with significantly lower food-specific IgE levels.

A 4.5 mm cut-off using the Skin Prick Automated Test showed comparable accuracy to the standard skin prick test in detecting birch pollen and house dust mite allergies.

This month in review spotlights 6 headlines, from the FDA approving sebetralsta for HAE to NICE Recommending Betula Verrucosa for Birch Tree Allergy.

An online course, AllergyAware, significantly improved school personnel’s ability to recognize and manage anaphylaxis.

New research finds patients with severe allergic asthma had greater emotional regulation than those with venom anaphylaxis, despite reporting poorer physical well-being.

The National Institute for Health and Care Excellence endorses betula verrucosa for long-term relief from severe birch tree allergies, such as allergic rhinitis or conjunctivitis.

A new study showed that cashew-induced anaphylaxis mostly affects children under 5 years, often from tiny amounts that are under a teaspoon.

A 2-step direct amoxicillin challenge safely ruled out penicillin allergy in low-risk pregnant patients, offering a faster alternative to skin testing.

Neffy showed fast symptom resolution in children experiencing moderate anaphylaxis following oral food challenges, offering a needle-free alternative to epinephrine injection.

Daily intake of baked milk significantly improved tolerance and immune markers in young children with baked milk tolerance, according to a 12-month study.

Shaker shares how allergist-immunologists can use brief CBT, motivational interviewing, and risk reframing to shift patients’ fear of their food allergies into confidence.

Ellis discusses new data showing EURneffy nasal spray delivers effective adrenaline even during allergic rhinitis, matching intramuscular injection.

With the FDA acceptance of the NDA, the agency has assigned a PDUFA target action date of January 31, 2026, and may require an Advisory Committee meeting for approval.

UK study finds atopic conditions, especially anaphylaxis, significantly raise the risk of anxiety, depression, OCD, and other mental illnesses in primary care patients.

Asthma and peanuts were identified as key risk factors for grade 4 anaphylaxis in a retrospective study, highlighting the need for tailored prevention.