The HCPLive Rheumatology condition center page is a comprehensive resource for clinical news and insights on rheumatologic disease. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for arthritis, gout, nr-AxSpA, and more.
September 18th 2024
Types of occupation did not significantly affect response to treatment.
Collaborating Across the Continuum™: The Role of Multidisciplinary Care in the Management of Patients with Exocrine Pancreatic Insufficiency
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Cases and Conversations™: Applying Best Practices to Prevent Shingles in Your Practice
October 16, 2024
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Tackling Inequities in IBD: Inclusive Solutions for Elevated Patient Care
October 26, 2024
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6th Annual Advanced Practice Collaborative
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SimulatED™: Personalizing Treatment Choices to Achieve Glycemic and Weight Management Goals
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Cases and Conversations™: Keeping Up with Novel Approaches to Managing ANCA-Associated Vasculitis
November 18, 2024
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Shaping the Management of COPD with Biologic Therapy
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Elevating Care for PAH: Applying Recommended Management Approaches to Maximize Outcomes
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Clinical Consultations™: Managing Depressive Episodes in Patients with Bipolar Disorder Type II
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Expert Illustrations & Commentaries™: Exploring the Role of Novel Agents for the Management of IgA Nephropathy
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Medical Crossfire®: Understanding the Advances in Bipolar Disease Treatment—A Comprehensive Look at Treatment Selection Strategies
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'REEL’ Time Patient Counseling: The Diagnostic and Treatment Journey for Patients With Bipolar Disorder Type II – From Primary to Specialty Care
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‘REEL’ Time Patient Counseling™: Navigating the Complex Journey of Diagnosing and Managing Fabry Disease
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Expert Illustrations & Commentaries™: Envisioning Novel Therapeutic Approaches to Managing ANCA-associated Vasculitis
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Clinical ShowCase™: Finding the Best Path Forward for Patients with COPD
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A Tethered Approach to Type 2 Diabetes Care – Connecting Insulin Regimens with Digital Technology
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Surv.AI Says™: What Clinicians and Patients Are Saying About Glucose Management in the Technology Age
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Clinical ShowCase™: Forming a Personalized Treatment Plan for a Patient With ANCA-Associated Vasculitis
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Addressing Healthcare Inequities: Tailoring Cancer Screening Plans to Address Inequities in Care
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SimulatED™: Diagnosing and Treating Alzheimer’s Disease in the Modern Era
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Patient, Provider & Caregiver Connection™: Implementing an Effective Management Plan to Improve Outcomes in IgA Nephropathy
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High ankle sprains require a high index of suspicion
December 1st 2008ABSTRACT: High ankle sprains are not as common as low anklesprains, but they are a significant injury, and the diagnosis may bechallenging. The primary role of the syndesmosis is to maintain therelationship of the talus to the tibia under physiological loads.Toaccomplish this, the distal tibiofibular joint must maintain its stability.The syndesmosis is injured most often with external rotation at theankle joint while the foot is dorsiflexed and pronated. On physicalexamination, tenderness is located in the area of the anterior syndesmosis.There are several special tests for syndesmosis injuries.Radiographic assessment is helpful. The usefulness of classificationsystems is not well defined. The optimal rehabilitation programis unknown. Rehabilitation generally is divided into phases.(J Musculoskel Med. 2008;25:564-569)
RA, cardiovascular disease, and diabetes links highlight conference
November 29th 2008Links between rheumatoid arthritis (RA) and cardiovascular disease (CVD) and diabetes mellitus (DM) highlighted the research findings reported at the recent American College of Rheumatology (ACR) Annual Scientific Meeting in San Francisco.
MRI for Evaluating Knee Pain in Older Patients: How Useful Is It?
October 29th 2008Knee pain is a common complaint in older patients, andosteoarthritis is the leading cause.We prospectively evaluated the diagnosticpatterns of nonorthopedic physicians in 100 consecutive patientsolder than 60 years who had knee pain. Our study shows thatthere is a lack of consensus about the use radiographic studies for diagnosisof knee pain in older patients.Weight-bearing radiographs areideal for evaluating knee pain. MRI frequently is overly sensitive in detectingpathology and often underestimates joint-space narrowingand arthrosis. MRI also represents a much larger cost and burden onthe health care system. MRI is indicated when the cause of knee painis not readily apparent after careful physical and radiographic evaluation.(J Musculoskel Med. 2008;25:500-504)
Heart failure differs in patients with RA
October 26th 2008The clinical presentation and outcome of heart failure differ significantly in patients who have rheumatoid arthritis (RA) and those who do not.The presentation of heart failure is more subtle in patients with RA, and mortality is significantly higher.
Osteoarthritis: 20 Clinical pearls
September 30th 2008ABSTRACT: Osteoarthritis (OA) is the leading cause of chronicdisability in older adults. A multitude of factors can contribute to thedisease process. Only a portion of patients who have radiographicevidence of OA have associated pain. Several conditions can mimicOA. Laboratory tests often contribute little to the diagnosis.Treatmentshould be tailored to individual patients. Exercises and joint protectiontechniques are the mainstays of treatment. Patient educationmay be beneficial. Acetaminophen and NSAIDs are effective in manypatients. Cyclooxygenase-2 inhibitors are associated with improvedGI tolerability. Glucosamine and chondroitin sulfate may produceimprovements in pain and function and may be associated with adecrease in the radiographic progression of OA. Corticosteroids canprovide symptomatic relief. Surgery is an option for advanceddisease. (J Musculoskel Med. 2008;25:476-480)
Differentiating low and high ankle sprains
August 28th 2008Differentiation between low and high ankle sprains iscritical to delivering appropriate care.The classic mechanism for a lowankle sprain is inversion and plantar flexion. A history of ankle ligamentinjury predisposes to recurring sprains. The ankle anterior drawertest may be used to evaluate ligamentous instability. Plain radiographsof the foot and ankle may be indicated in a patient who has an acuteankle injury. Clinicians often use the Ottawa ankle rules to determinethe need for radiographs. In the acute phase, the goals of treatment areto alleviate pain, reduce swelling, and protect the ankle from furtherinjury. NSAIDs and rehabilitation are important components of management.Primary prevention may be possible with strengthening andbalance programs. (J Musculoskel Med. 2008;25:438-443)
Identifying and Managing Dermatomyositis: A Case Report and Review
August 25th 2008This detailed review desccribes the heterogeneous idiopathic inflammatory myopathies and their mimics, with criteria for classification, an overview of cardiac, pulmonary and malignant comorbidieis, and guidance for treatment.
Disease outcome prediction rule for arthritis validated
August 22nd 2008A prediction rule for the development of rheumatoid arthritis (RA) in patients with undifferentiated arthritis (UA) has been validated. The rule accurately estimates the risk of RA in more than 75% of patients with recent-onset UA.
Perilunate dislocation: Case studies of a frequently missed diagnosis
July 28th 2008ABSTRACT: If enough force is applied in a wrist ligament injury, aperilunate dislocation may occur. Physicians can readily make thediagnosis, but the injury may be missed in the initial evaluation. Withprompt recognition and intervention, the incidence of permanentdisability may be lessened. Acute carpal tunnel syndrome may accompanyperilunate injuries and frank dislocations. The scapholunateand lunotriquetral ligaments confer significant structural stabilityand help maintain the anatomical relationships of the carpal bones;when they are compromised, structural integrity is lost.Visual inspectionis critical to the physical examination. Neurovascular statusshould be determined and documented. Radiographic evaluationis recommended for all hand injuries. All perilunate dislocationsfirst need to be closed reduced, followed by surgical treatment.(J Musculoskel Med. 2008;25:390-395)
Differentiating osteopoikilosis from osteoblastic metastases
July 27th 2008ABSTRACT: Osteopoikilosis is a rare, benign osteosclerotic dysplasiathat predominantly involves the appendicular skeleton. Radiographicfindings are diagnostic, and the disease often is discovered incidentallyon x-ray films. The importance of recognizing osteopoikilosis liesin differentiating it from osteoblastic metastases. The cause is unclear.Patients typically are asymptomatic. Diagnostic findings include theappearance of numerous small,well-defined, spheroid sclerotic foci.Because evidence suggests an association with skeletal and dermatologicalchanges, evaluation for coexisting pathological conditions maybe warranted. The differential diagnosis for a patient who has radiographiccharacteristics similar to those of osteopoikilosis includes osteoblasticmetastases, mastocytosis, tuberous sclerosis, melorheostosis,and osteopathia striata. (J Musculoskel Med. 2008;25:387-389)
Corticosteroids for painful shoulder conditions: Injection techniques
July 26th 2008ABSTRACT: Corticosteroid/anesthetic injections may be useful diagnosticand therapeutic tools for painful shoulder conditions. The currentdogma is to avoid performing more than 3 injections over a9- to 12-month period, but this rule may be broken. The volume of localanesthetic typically injected might be insufficient for assessing accuracy.Data demonstrating significant advantages of one corticosteroidover another are scarce. For patients with diabetes mellitus, considera somewhat insoluble phosphoric corticosteroid. There is no consensusabout appropriate dosages and techniques.We recommend using1.5-inch 25-gauge needles for most injections. Re-evaluating provocativemaneuvers after each injection is important. The patient's estimatedpain relief always should be documented.Two approaches toinjection may be used, an advanced/detailed method and abasic/quick method. (J Musculoskel Med. 2008;25:375-386)
Questions about tolerance with use of opioids
July 23rd 2008I was very interested in the article "Chronic pain update: Addressing abuse and misuse of opioid analgesics" by Ross et al (The Journal of Musculoskeletal Medicine, June 2008, page 268) because pain management and addiction medicine is my specialty.The article was interesting, useful, and well written and referenced. However, it perpetuated one myth about opioid prescribing for chronic pain when the authors wrote, "Tolerance develops in most patients who receive long-term opioid therapy."
High Birth Weight Leads to Rheumatoid Arthritis in Adulthood
July 3rd 2008The fetal environment potentially preprograms the brain or endocrine system to be maladapted later in life and that patients with rheumatoid arthritis are known for having a dysregulated HPA axis, which may be affected in utero.
Injection of the anserine bursa and iliotibial tract
June 26th 2008ABSTRACT: Inflammation of the anserine bursa occurs frequently inathletes who have tight hamstrings, obese patients, patients who haveknee joint pathology, and those who experience direct trauma to thearea. Iliotibial band syndrome results from inflammation of the iliotibialtendon and the bursa. For both injections, the patient may beinjected while lying supine with the leg extended. During anserinebursa injection, the lidocaine and corticosteroid should flow withoutresistance, although some pressure is required. An inability to depressthe syringe plunger requires repositioning of the needle to avoid injectioninto the medial collateral ligament or pes anserinus tendons.(J Musculoskel Med. 2008;25:340-341)
New RA therapy recommendations cover 5 domains
June 23rd 2008Most patients with a confirmed diagnosis of rheumatoid arthritis (RA) use nonbiologic disease-modifying antirheumatic drugs (DMARDs), and the rate of biologic DMARD use is increasing rapidly, according to the American College of Rheumatology (ACR).The organization last updated recommendations for the use of nonbiologic DMARDs in 2002 and had not developed recommendations for using biologic agents.
Addressing patellofemoral pathology: Biomechanics and classification
May 28th 2008There is no clear consensus about which therapiesshould be used for the various underlying pathologies that lead topatellofemoral problems. The major distinction in classification isbetween patellofemoral compression syndrome and patellofemoralinstability. Patients with the former are concerned primarily withpain; those with the latter have instability or pain or both. Patellarpain may manifest in the parapatellar area or radiate to the back ofthe knee. Persons' differing activity and conditioning levels maylead to patellofemoral pain variability. Patients with patellar instabilityinclude those with recurring frank patellar dislocations andthose with symptoms of subluxation. Patients who have patellar instabilitypresent with tears of the medial patellofemoral ligament;this is the "essential lesion" for patellar dislocation. (J MusculoskelMed. 2008;25:297-300)