Publication

Article

Internal Medicine World Report
July 2005

Silent Myocardial Ischemia Common in Stroke, TIA Patients

Silent Myocardial Ischemia

Common in Stroke, TIA Patients

More than half of patients with symptomatic intracranial atherosclerosis have silent myocardial ischemia. A group of 65 patients with a first-ever transient ischemic attack (TIA) or ischemic stroke underwent maximal-stress myocardial perfusion single-photon emission computed

tomography (SPECT). Reversible myocardial perfusion defects occurred in 34 (52%) patients. Risk factors associated with a pathologic SPECT included elevated total cholesterol, lipoprotein(a), and homocysteine levels. Having a stenosed intracranial internal carotid

artery and the symptomatic stenosis being located in vertebrobasilar arteries

were independently associated with silent myocardial ischemia after accounting

for other risk factors (Stroke.2005;36:1201-1206).

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