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Sex differences in the development of higher systolic blood pressure during adolescenceWe evaluated the differences in higher systolic blood pressure (SBP) between boys and girls in a longitudinal adolescent cohort. Results showed that although boys have a 19% relative increase in the risk of higher SBP annually between the ages of 13 and 17 years, girls do not experience the same risk increase. Among both boys and girls, being overweight increases the likelihood of high SBP almost 3-fold, and every 5 additional hours of "screen time" (television viewing, video game playing, Internet use) is associated with a 4% relative increase in the likelihood of higher SBP levels. For every 5 additional sports-related or other active behaviors over a 7-day recall, there was an 8% relative reduction in high SBP risk. Annual blood pressure assessment in teens that continues into adulthood may facilitate early detection of adult hypertension. Weight control, increased physical activity, and reduced screen time may reduce the likelihood of higher SBP levels developing in adolescents.
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How Population Rates Dictate the Geriatric Healthcare MarketIncreasing life expectancy from improved healthcare has directly influenced the avenues by which elderly people seek aid and care.
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What Should I Prescribe for This Man's Depression?Several factors should be considered when choosing a medication and dosing schedule for this depressed adult male who reports being "very sensitive" to medication and expresses particular concern about being either sedated or "revved up" from an antidepressant.
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Developing Long-Term and Effective Collaborations with Patient Advocacy GroupsWhen successful, these relationships provide valuable insights to support strategies in many areas, including planning for clinical research, patient recruitment and education, reimbursement, access, compliance, and other areas.
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Anti-inflammatory effects of pioglitazone and/or simvastatin in patients with distinct clinical risk for cardiovascular complicationsStatins are the most commonly used pharmacologic intervention in patients with increased cardiovascular risk. In addition to their beneficial effect on the atherogenic lipid profile, they have been shown to exert several pleiotrophic effects, including the reduction of low-grade inflammation. Thiazolidinediones (TZDs) are a new class of antidiabetic drugs that have been shown to improve insulin sensitivity and to reduce cardiovascular risk in patients with type 2 diabetes. Our study is the first to show a complementary effect of TZD and statin treatment on several cardiovascular risk factors in subjects without diabetes. These findings may have important implications for further discussion on cardiovascular risk reduction, especially for patients with metabolic syndrome.
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Sudden death in patients with myocardial infarctionWe evaluated the risk and timing of sudden death among high-risk patients after myocardial infarction (MI). Among survivors of acute MI with reduced left ventricular systolic function or heart failure, or both, the risk of sudden death from cardiac causes was highest in the first 30 days after MI. These findings indicate a need for early intervention to prevent sudden death during this vulnerable period.
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Top 5 Rare Disease News of the Week—September 23, 2018Stay up-to-date on the latest rare disease news by reading the top 5 articles of the week.
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Smoother Care Transitions Cut Readmissions for OPAT PatientsReadmission reduction has the potential for broad impact, especially in disadvantaged populations.
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The Doctor is in… the KitchenDr. Tim Harlan didn't come to medicine the traditional way. At age 22, when most of his colleagues were plunging into their first year of medical school and comparing their impressive pre-med resumes, Harlan was opening a restaurant.
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Systematic Review Suggests Oral JAK Inhibitors Effective in ADOral doses of 3 Janus kinase inhibitors show the therapies out-performed placebo in all outcomes measured in patients with moderate-to-severe AD.
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Annual Mammography Not Superior to Standard Care on Breast Cancer MortalityMammography screening has conflicting efficacy results in the medical literature, as some clinical studies have shown little or no effect, while others have demonstrated decreased mortality in women aged 40 and older, with the largest effect in those aged 50-59 years.
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OCR Issues Proposed Modifications to HIPAA Privacy and Security Rules to Implement HITECH ActOn July 14, 2010, the Office for Civil Rights (OCR) of the U.S. Department of Health and Human Services (HHS), issued a proposed rule containing modifications to the privacy standards, security standards, and enforcement regulations under HIPAA.
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Adherence to ACS Medications: A Path Forward for Improved Patient CareOne study has shown that 90-day prescriptions can increase adherence over 30-day prescriptions.
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Large-scale clinical epidemiology of stable angina in women and menWe performed a whole-country study using linked health care records in Finland and showed that stable angina as the initial symptomatic manifestation of coronary disease occurs as frequently in women as it does in men. Among easily recognized subgroups, the absolute rates of prognostic outcomes were similarly high in women and men.
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Cancer-Killing Virus Looks PromisingIn March, the television news show 60 Minutes devoted a segment to a clinical trial using polio virus to treat glioblastoma multiforme. The segment called "Killing Cancer" did a good job of illustrating the potential power of this new treatment as well as the problems associated with glioblastoma multiforme which typically kills patients in a matter of months.
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AAP 2011: Minority Children Less Likely to Wear a Car Seatbelt, Putting Them at Greater Risk of Severe InjuryLess than half of pediatric car passengers suffering injuries from motor vehicle crashes were restrained, with the lowest rates among blacks, Hispanics and Native Americans, according to a research abstract presented at AAP 2011.
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Contemporary stenting practices, optimal antiplatelet and antithrombotic therapy, and the continuum of care of patients with cardiovascular disease: A roundtable discussionThe first stent was invented in 1969 by Charles Theodore Dotter, experimenting on canine peripheral arteries.
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After House Passage 21st Century Cures Act Awaits Senate ApprovalWith funding meant to bolster basic research and help make advances for a variety of conditions the fate of the 21st Century Cure Act is anything but secure even after passage by the US House of Representatives.
