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White-coat hypertension and progression to home hypertensionOur study aimed to clarify whether white-coat hypertension represents a transient state in the development of hypertension outside medical settings. We followed up 128 subjects with white-coat hypertension and compared their risk of progression to home hypertension with that of 649 sustained normotensive subjects. After 8 years of follow-up, subjects with white-coat hypertension had an approximately 3-fold higher risk of eventually manifesting home hypertension. We concluded that patients with white-coat hypertension should be carefully monitored.
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Raise Your Hand to Stop Diabetes®In honor of Diabetes Awareness Month, the ADA put together video clips of health care professionals pledging to stop diabetes.
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The HITECH Act Is ConstitutionalArguments that the EHR-implementation incentives under the HITECH Act are unconstitutional fail for a variety of reasons.
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The cost of failureWhen considering the article by Goldberg and colleagues, it seems reasonable to request a change in the title to "Survival after the diagnosis of  heart failure."
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Tardive Dyskinesia: Clues to the Diagnosis and TreatmentTardive dyskinesia is a common problem associated with the long-term use of potent antipsychotic drugs. It has become less common with the increased use of the newer atypical antipsychotic medications. The condition is manifested by abnormal orofacial, extremity, and sometimes trunk movements. Decades after it was first identified, our understanding of the pathophysiology of tardive dyskinesia remains incomplete, and currently no definitive treatment is available. Encouraging advances in recent years point to promising new treatment options. This article discusses factors that may predispose to tardive dyskinesia as well as the latest developments in treatment.
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Alcohol consumption in men with hypertensionWe assessed the association between the incidence of coronary heart disease and alcohol consumption among hypertensive men enrolled in the Health "Professionals" Follow-Up Study. Moderate alcohol consumption (1 to 2 drinks per day) was associated with a lower risk of myocardial infarction, as in the general population, but was not associated with the risks of stroke, total mortality, or mortality from cardiovascular causes. These results show that men with hypertension who drink moderately may not need to change their drinking habits.
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How do cardiac and noncardiac conditions affect survival after ICD implantation?The benefits of implantable cardioverter-defibrillators (ICDs) have been shown in randomized clinical trials. The factors that affect the risk–benefit ratio in a community setting, however, have not been evaluated.
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Inflammation, heart failure, and mortality in survivors of acute myocardial infarctionWe prospectively studied the relationship between C-reactive protein, obtained within 12 to 24 hours of symptom onset, and long-term risk of death and heart failure in survivors of acute myocardial infarction. The risk of death and heart failure increased progressively with increasing quartiles of C-reactive protein. We found a graded positive relationship between C-reactive protein levels and post-discharge mortality and heart failure.
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Treat-and-Extend Regimen Proves Preventive of Long-Term Vision Loss in AMDThese regimens can also ensure the maintenance of visual acuity levels that can keep patients self-sufficient in real-world scenarios, such as driving, reading, and recognizing faces.
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Opinion: With an Opioid Epidemic, We Can't Afford to Cut Addiction Treatment ServicesConstance Scharff, PhD: it's a bad time to cut access.
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Chronic diuretic use and increased mortality and hospitalization in heart failureDiuretic use is associated with activation of neurohormones and disease progression in heart failure. Yet, diuretics are commonly prescribed, although little is known about their long-term effects. We performed a study based on propensity score matching, which indicated that in subjects with ambulatory, chronic, mild-to-moderate heart failure, diuretic use was associated with increased mortality and hospitalization. These findings call into question the wisdom of using long-term diuretic therapy in heart failure patients who are asymptomatic or minimally symptomatic.
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Increased Mortality Associated with Digoxin in AF PatientsAlthough digoxin has a very long clinical history, no randomized controlled trial has evaluated the use of digoxin for atrial fibrillation (AF). Therefore, the evidence for its use in AF is based on post hoc analyses of RCTs or on findings from observational studies. Several studies have shown the association of digoxin use with increased mortality rates. However, other studies have reported the opposite conclusions, and it remains controversial whether digoxin use is associated with increased mortality in patients with AF.
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Multidrug Resistant Infections: Is the Clinical Infection Treatment Pathway Outdated?The current treatment paradigm might need to evolve to adjust to rapid diagnostics and narrowing down the antibiotics to aid in optimal outcomes for sicker patients with gram-negative infections.
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How Tweet it Is - A Look Back at the Year in Healthcare Social Media2009 may very well be looked back on as the year that social media �nally came into its own in healthcare. Compared to how things were a couple years ago, the current level of penetration, acceptance, and utilization of social media tools of all stripes within healthcare is striking. Here, we present summaries of some of the biggest stories and trends in healthcare social media from 2009.
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Contemporary cardiac imaging in hypertrophic obstructive cardiomyopathyFeatures of hypertrophic obstructive cardiomyopathy (HOCM) include obstruction at the left ventricular outflow tract (caused by a markedly thickened proximal interventricular septum) and systolic anterior motion of the mitral valve. The case discussed here illustrates several classic features of this disease including clinical presentation, diagnostic workup, and noninvasive and invasive management.
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Anxiolytic and Hypnotic Drugs Increase Risk of DeathA recent study has raised concerns about the use of prescribed anxiolytic and hypnotic drugs, especially given their addictive nature.
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Psychiatry Becomes Individual with Better Screening, More TherapiesBy screening during primary care visits, patients are now more aware than ever about their possibility of depression and other mental health disorders.
