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Historic Phase 3 Microbiota Trial for C Diff Treatment Completes EnrollmentRBX2660 from Rebiotix will be assessed in a randomized study involving 300 patients.
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Iatrogenic dilated cardiomyopathy and spectrum of current treatment modalitiesOur increasing ability to intervene in high-risk patients—with lower risks and greater chances for successful outcomes—is felt across the broad spectrum of cardiovascular disease. This is particularly evident in patients with dilated cardiomyopathy (DCM).
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Updated Recommendations for Gestational Diabetes Streamline Screening MethodsIn response to the growing prevalence of gestational diabetes mellitus and its associated morbidities, much attention has been paid to the use of appropriate screening methodologies for the metabolic disorder.
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The role of angiotensin-converting enzyme inhibitors in patients with stable coronary artery disease and preserved left ventricular systolic functionAngiotensin-converting enzyme (ACE) inhibitors have been shown to be beneficial in the management of multiple cardiovascular disease states.
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Nonischemic cardiomyopathy and implantable cardioverter-defibrillatorsWe assessed whether duration of nonischemic cardiomyopathy was related to the degree of benefit from implantable cardioverter-defibrillator (ICD) insertion. Subjects who had a recent diagnosis of nonischemic cardiomyopathy had at least a similar benefit from ICD insertion as did those with a remote diagnosis. These results indicate that ICD therapy should be considered in such patients as soon as they are diagnosed and once reversible causes of left ventricular dysfunction have been excluded.
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Is warfarin a safe alternative to aspirin in elderly patients with atrial fibrillation?We recruited 973 patients (mean age, 81 years) with atrial fibrillation from the primary care setting and randomly assigned them to receive anticoagulation with warfarin or aspirin.
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Psychological Factors May Explain Treatment Gaps for Patients with DepressionConflicts between identity and depressive symptoms may account for the significant delays in help-seeking by patients with depression, according to research published October 2, 2012 in BMC Psychiatry.
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The time has come for ethnicity-specific CV risk calculatorsThe risk calculator reported in the Lee et al paper was developed to predict the 10-year cardiovascular (CV) disease probability in an American Indian population.
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Opioids Not a Good Idea for Lower Back PainAdding opioids or skeletal muscle relaxants to traditional nonsteroidal anti-inflammatory drug (NSAID) treatment for acute lower back pain (LBP) provides little improvement in pain management,
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Navy Medicine: A Strategic Roadmap for Implementing a Virtual Mental Health ProgramA military service member talks about some of the ways the Navy is implementing new programs to improve mental health conditions.
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Diffuse Myocardial Fibrosis Is Associated With Diastolic Dysfunction in HF with Preserved EFIs degree of diffuse myocardial fibrosis associated with severity of diastolic dysfunction in heart failure with preserved ejection fraction?
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Choice of imaging modality for evaluation of myocardial ischemia—what is the bottom line?In Jahnke et al's study, the authors showed the prognostic value of yet another imaging modality—perfusion magnetic resonance (MR) imaging and dobutamine stress MR.
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Early statin therapy in acute coronary syndromePatients who survive an acute coronary syndrome are at much higher risk of a recurrent event within the following month than patients with stable coronary syndromes. Statin therapy lowers the risk of recurrent events for many years but also reduces the risk of another event within the weeks to months following the initial acute coronary syndrome. The mechanisms that contribute to this benefit are likely related to improved endothelial function, decreased vascular inflammation, and reduced prothrombotic factors. Observation studies show an early reduction in mortality with statin therapy started before discharge from the hospital after an acute coronary syndrome.
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Undiagnosed diabetes mellitus in coronary artery bypass graft surgeryWe examined the prevalence and risks associated with undiagnosed diabetes mellitus among more than 7000 patients who had undergone coronary artery bypass graft surgery. At the perioperative and postoperative stages, patients with undiagnosed diabetes showed a significantly higher morbidity and mortality rate.
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Give the Old Guys a Chance: Remembering Older InsulinsI have not had a recent referred patient come to me on any older insulins. The big surprise? Many times I switch them back from Aspart, Levemir, and lantus.
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HMG-CoA reductase inhibitors and diabetic retinopathyIncreased serum lipid levels in diabetic patients are associated with an increased risk of macular edema, retinal hard exudates, and secondary visual loss.
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Cutting the Cord: The Guide to Wireless PracticeIs a wireless practice right for you? If so, what components would benefit you most, and what should you know about them before making the jump?
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The Industry Insider: May 2007News and information from the pharmaceutical industry. In this issue: 1) Multiple Deals for Affitech 2) Pfizer's Sutent Wins European Association of Urology Support 3) Aurora Breast MRI Will Meet Surge in Screening Demand 4) Two New Products for VioQuest 5) Cytyc and Quest Sign Multi-Year Agreement 6) Calando's Lead RNAi Candidate Shows Anti-Cancer Effect
