Ophthalmology

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In a new study, stroke occurred in 6.6% of the ranibizumab-treated group, compared with 7.0% of the controls matched by sociodemographic factors and comorbidities and 6.7% of the controls matched by sociodemographic factors only. These differences were not statistically significant.

A Spanish research team found an association between testing positive for antibodies to adalimumab (Humira) and a worse outcome of uveitis, but only in those who tested positive permanently. They also found that this association correlated with undetectable trough levels of Humira.

Adalimumab (ADA) works well as a treatment for patients with both active and inactive uveitis whether or not they are taking an immunosuppressant (IMM); however, the median time to treatment failure (mTTF) is longer for patients with inactive uveitis taking an IMM.