On the HCPLive Ophthalmology page, resources on the topics of medical news and expert insight into ophthalmic disease can be found. Content includes articles, interviews, videos, podcasts, and breaking news on eye disease research, treatment, and drug development.
February 6th 2025
The January 2025 ophthalmology month in review highlights the latest from the FDA, key updates to the ophthalmic pipeline, and the latest episode of New Insight.
January 31st 2025
For Bilateral Uveitic Glaucoma, It May be Best to Operate on Second Eye Sooner than Later
A retrospective review of patients with bilateral uveitic glaucoma who had filtration surgery in both eyes at different times found that the second surgically treated eye showed greater glaucomatous disc progression than the first.
Antibody Development an Obstacle in Treating Uveitis with Humira
A Spanish research team found an association between testing positive for antibodies to adalimumab (Humira) and a worse outcome of uveitis, but only in those who tested positive permanently. They also found that this association correlated with undetectable trough levels of Humira.
No Tool Yet To Identify Visual Impairments after Strokes
Despite the fact that two thirds of stroke survivors could suffer from a visual impairment, nearly half of stroke units do not even assess vision. A recent report suggests that more must be done to assess the outlook for vision in stroke survivors.
Mediterranean Diet May Deter Macular Degeneration
A recent study joins an ever-deepening well of data about the health benefits of the Mediterranean diet, including its risk-reduction potential for age-related macular degeneration. AMD is the leading cause of blindness in the developed world.
Diabetic Macular Edema Study: Ozurdex Outperformed Avastin, but Not Without Drawbacks
Monthly Avastin injections and quarterly Ozurdex injections produced equivalent improvements in best-corrected visual acuity after 7 months. However, Ozurdex reduced central subfield thickness nine times more than Avastin did, though it was associated with elevated intraocular pressure.
Uveitis: Pediatric Patients Did Fine on Adalimumab
Adalimumab has the potential to serve an important role in management of chronic and refractory noninfectious uveitis and associated macular edema with low rates of serious adverse events in the long term, according to a recent report. That includes pediatric patients.
Immunosuppressants Help Extend Treatment Effect in Uveitis
Adalimumab (ADA) works well as a treatment for patients with both active and inactive uveitis whether or not they are taking an immunosuppressant (IMM); however, the median time to treatment failure (mTTF) is longer for patients with inactive uveitis taking an IMM.
Patients See Benefits of Technological Advances in Ophthalmology
As with most surgical advances, new potential procedures in ophthalmology pose their fair share of risks. However, if those risks can be overcome the rewards to patients can make a significant difference in their quality of life.
Finding New Uses for ARGUS Technology in Age-Related Macular Degeneration
As a retinal implant, the ARGUS II technology has shown early benefits for patients with retinitis pigmentosa. A new study from the United Kingdom is examining its benefits in patients with the dry form of age related macular degeneration.
Weighing Safety Risks and Efficacy of New Vitrectomy Procedure Option
As with all new technologies for surgical procedures, there will be questions to be answered about the safety for hypersonic vitrectomy. While human trials have not started yet, there are good indications in cadaveric and animal studies.
Alzheimer's Disease Proteins Could Be the Leading Cause of Age-related Macular Degeneration
Scientists found that amyloid beta proteins accumulate in the retinas of AMD patients – the same types of proteins that settle in the brains of people with Alzheimer’s disease.
High-Fat Diets Alter Gut Microbiota, Leading to Increased Choroidal Neovascularization
Research using mouse models demonstrated that a high-fat diet increased intestinal permeability, which led to increases in circulating and local inflammatory cytokines, and increased choroidal neovascularization.
Subretinal Gene Therapy Improves Vision in Patients with Wet Age-Related Macular Degeneration
Treatment with recombinant adeno-associated virus vector gene-therapy was shown to be safe and potentially effective in a small test group of patients with neovascular age-related macular degeneration.
Women With Spondyloarthritis Face Increased Risk of Uveitis, Other Conditions
A new study out of Ireland examined the prevalence of extra-articular manifestations in axial spondyloarthritis, and found that women were at significantly higher risk for inflammatory bowel disease and uveitis than men.