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This Year In Medicine 2025

Opinion|Videos|September 4, 2024

Reconsidering Standard of Care for Hypercortisolism

Author(s)Natalie Bellini, DNP, FNP-BC, BC-ADM, CDCES, Ralph DeFronzo, MD , Athena Philis-Tsimikas, MD

Panelists discuss how treating hypercortisolism in patients may have long-term effects on glycemic control and overall health, potentially influencing future standards of care for difficult-to-control Type 2 diabetes, while emphasizing the need for clinicians to carefully manage such patients as ongoing research continues.

Episodes in this series

EP. 1 Overview of the CATALYST Study for Hypercortisolism

EP. 1 Overview of the CATALYST Study for Hypercortisolism

EP. 2 Defining Difficult to Control Diabetes

EP. 2 Defining Difficult to Control Diabetes

EP. 3 CATALYST Trial Study Design

EP. 3 CATALYST Trial Study Design

EP. 4 True Prevalence of Hypercortisolism

EP. 4 True Prevalence of Hypercortisolism

EP. 5 Coexisting Cardiometabolic Conditions and Hypercortisolism

EP. 5 Coexisting Cardiometabolic Conditions and Hypercortisolism

EP. 6 Engaging Primary Care Clinicians in Screening for Hypercortisolism

EP. 6 Engaging Primary Care Clinicians in Screening for Hypercortisolism

EP. 7 Spectrum of Hypercortisolism Presentations

EP. 7 Spectrum of Hypercortisolism Presentations

EP. 8 Mifeprestone for Treatment of Hypercortisolism

EP. 8 Mifeprestone for Treatment of Hypercortisolism

EP. 9 Reconsidering Standard of Care for Hypercortisolism

EP. 9 Reconsidering Standard of Care for Hypercortisolism

Video content above is prompted by the following:

For patients undergoing treatment for hypercortisolism, what are the long-term implications for glycemic control and overall health?
How might future findings from this study influence the standard of care for patients with difficult-to-control T2D?
Part 2 of this study is currently ongoing. In the meantime, how should clinicians be approaching patients who meet these criteria right now?

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