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This Year In Medicine 2025

Opinion|Videos|August 28, 2024

Spectrum of Hypercortisolism Presentations

Author(s)Natalie Bellini, DNP, FNP-BC, BC-ADM, CDCES, Ralph DeFronzo, MD , Athena Philis-Tsimikas, MD

Key opinion leaders explore the diverse clinical manifestations of hypercortisolism across its spectrum of presentations.

Episodes in this series

EP. 1 Overview of the CATALYST Study for Hypercortisolism

EP. 1 Overview of the CATALYST Study for Hypercortisolism

EP. 2 Defining Difficult to Control Diabetes

EP. 2 Defining Difficult to Control Diabetes

EP. 3 CATALYST Trial Study Design

EP. 3 CATALYST Trial Study Design

EP. 4 True Prevalence of Hypercortisolism

EP. 4 True Prevalence of Hypercortisolism

EP. 5 Coexisting Cardiometabolic Conditions and Hypercortisolism

EP. 5 Coexisting Cardiometabolic Conditions and Hypercortisolism

EP. 6 Engaging Primary Care Clinicians in Screening for Hypercortisolism

EP. 6 Engaging Primary Care Clinicians in Screening for Hypercortisolism

EP. 7 Spectrum of Hypercortisolism Presentations

EP. 7 Spectrum of Hypercortisolism Presentations

EP. 8 Mifeprestone for Treatment of Hypercortisolism

EP. 8 Mifeprestone for Treatment of Hypercortisolism

EP. 9 Reconsidering Standard of Care for Hypercortisolism

EP. 9 Reconsidering Standard of Care for Hypercortisolism

Video content above is prompted by the following:

Can you discuss the spectrum of hypercortisolism and its various clinical presentations, especially in T2D?
Based on the prevalence data from the CATALYST study, how should we approach screening of patients for hypercortisolism?
Are there specific subgroups of patients with T2D who may have a higher prevalence of hypercortisolism?
Can you talk about testing for hypercortisolism? What tests are recommended for screening and subsequent confirmation?
Can you explain the dexamethasone suppression test (DST) used in the CATALYST study?

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