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Spotlight -

This Year In Medicine 2025

Opinion|Videos|March 1, 2025

Impact of GPP Triggers and Flares on a Patient’s Physical and Mental Health

Author(s)Aaron Farberg, MD, FAAD , Harrison Nguyen, MD, MBA, MPH, FAAD , Boni Elewski, MD, FAAD

Panelists discuss the physical and mental health challenges of generalized pustular psoriasis (GPP), common flare triggers, the varying severity of flares, and the importance of timely treatment to prevent severe complications.

Video content above is prompted by the following:

Episodes in this series

EP. 1 Clinical Presentation and Burden of Disease of Generalized Pustular Psoriasis

EP. 1 Clinical Presentation and Burden of Disease of Generalized Pustular Psoriasis

EP. 2 Impact of GPP Triggers and Flares on a Patient’s Physical and Mental Health

EP. 2 Impact of GPP Triggers and Flares on a Patient’s Physical and Mental Health

EP. 3 Approaches to Diagnosing GPP and Distinguishing It From Other Psoriatic Conditions

EP. 3 Approaches to Diagnosing GPP and Distinguishing It From Other Psoriatic Conditions

EP. 4 Challenges for Making a Timely GPP Diagnosis

EP. 4 Challenges for Making a Timely GPP Diagnosis

EP. 5 GPP Pathogenesis and Treatment Goals

EP. 5 GPP Pathogenesis and Treatment Goals

EP. 6 Older Treatment Approaches to GPP Management

EP. 6 Older Treatment Approaches to GPP Management

EP. 7 Addressing the Psychosocial Aspects of GPP Management and the Role of Multidisciplinary Care

EP. 7 Addressing the Psychosocial Aspects of GPP Management and the Role of Multidisciplinary Care

EP. 8 Role of IL-36 in GPP Pathogenesis and Treatment

EP. 8 Role of IL-36 in GPP Pathogenesis and Treatment

EP. 9 Overview of Spesolimab for Management of GPP

EP. 9 Overview of Spesolimab for Management of GPP

EP. 10 Utilizing Intravenous and Subcutaneous Formulations of Spesolimab

EP. 10 Utilizing Intravenous and Subcutaneous Formulations of Spesolimab

EP. 11 Future Directions for GPP Management and Key Takeaways

EP. 11 Future Directions for GPP Management and Key Takeaways

How do you talk to your patients with GPP about their physical and mental health?
What are some common triggers of GPP flares? How do you discuss identifying and managing triggers with your patients?
Discuss the physical impact of GPP flares on a patient. How can GPP flares differ in severity from patient to patient and even from flare to flare?
What are some severe complications that can arise from GPP flares, and how important is it to treat GPP flares in a timely manner?

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