
Opinion|Videos|March 29, 2025
Utilizing Intravenous and Subcutaneous Formulations of Spesolimab
Panelists compare the results of the EFFISAYIL-1 and -2 trials with real-world use of spesolimab; discuss treatment expectations with patients; and explore the similarities, differences, and management roles of intravenous (IV) and subcutaneous (SQ) formulations, with strategies for timely IV therapy initiation during flares.
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Video content above is prompted by the following:
Episodes in this series

- How do the results of EFFISAYIL-1 and -2 compare with the results you have seen with spesolimab in clinical practice?
a. How do you discuss treatment expectations for spesolimab with your patients? - Discuss the utility of both an IV and SQ formulation of spesolimab. How are they similar and different, and how are both formulations used in the management of GPP?
a. PK modeling (Hawkes, 2024)
b. How do you ensure timely initiation of IV therapy and continuity of care when a patient is experiencing a flare?
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