Allergy

A recent study in Finland finds 2 major contributing factors to allergic disease in infants with familial risk.

In particular, airway epithelial cells (AEC) in allergic asthmatic (AA) were shown to upregulate mucus metaplasia, matrix-remodeling, and glycolytic programs while failing to upregulate antioxidant genes.

Dr. Christine Rauscher details immunotherapy for seasonal allergies, which affect roughly 20 millions adults in the US

Children with unconfirmed PALs have prolonged hospital stays, higher rates of adverse events, and more infections due to Clostridium difficile and vancomycin-resistant Enterococcus.

Up to 100 participants who experienced an allergic reaction to the vaccine will be enrolled in the single-site trial, which will be led by Dr. Pamela A. Guerrerio

The novel technology combines daily disposable contact lenses with ketotifen in a first in its new category approval.

The algorithm also resulted in a large reduction in oral food challenges.

Additionally, the association between atopic dermatitis and sensitization to eggs was more common during the pandemic then in years prior.

By blocking certain neurogenic changes that occur in the lungs at childhood, patients may avoid asthma and allergic responses into adulthood.

Currently, antibiotics comprise roughly 80% of prescribed pregnancy medications, and recent epidemiological studies have indicated a link between antibiotic use and dysbiosis.

Dr. Mathias noted that investigators are continuing to determine if age plays a role in peanut allergy risk and sensitization.

This decision could further exacerbate health inequities among populations that are socioeconomically disadvantaged.

Patients with allergic asthma could often have no clinical history of atopic dermatitis.

Most cases had onset after 4 hours and were mild, which Dr. Anvari noted should not contraindicate future COVID-19 vaccine doses.

In data presented at AAAAI 2022, investigators examined anaphylaxis rates in Brooklyn between 2016-2019.

Investigators from the Cincinnati Children’s Hospital Medical Center tested a new allergic reaction severity grading system.

Dr. Epstein provides updates on a joint study between members of AAAAI and the American College of Allergy on the relationship between epinephrine and post-immunotherapy injection waiting periods.

Urticaria and angioedema with oral mucocutaneous involvement were commonly labeled as anaphylaxis upon presentation.

The proportion of anaphylaxis episodes was higher in the cohort of patients with peanut allergies, compared to a control group of patients with non-peanut food allergies.

Dr. Zein speaks of the relationship between eosinophil count and COVID-19 illness and mortality, especially as it related to inhaled corticosteroid use.

The American College of Allergy, Asthma, and Immunology identify key practices for addressing allergies during the COVID-19 pandemic.

Data pooled from 5 trials show a consistent and manageable safety profile for continued treatment with PALFORZIA.

Prior studies have predominantly considered the associations of respiratory allergy and skin allergy in patients with ADHD, with inconsistent data on food allergy.

Rebecca Rosenberger discusses allergic and non-allergic triggers, and how patients with food allergies can avoid allergic reactions through the winter season.

Allergists discuss the differing opinions of allergies and optimizing patient care during the COVID-19 pandemic.