FDA Approves Ubrogepant for Acute Migraine in Adults
The oral CGRP antagonist becomes the first in its class approved for the indication.
FDA Approves Lemborexant for Insomnia in Adults
The small molecule orexin receptor antagonist will be made available for the US market in 2 different doses, in 2020.
FDA Approves Golodirsen Injection for DMD with Genetic Mutations
The approval comes 4 months following a Complete Response Letter was submitted and successfully disputed, to Sarepta Therapeutics.
FDA Approves Botox for Lower Limb Spasticity in Pediatric Patients
The FDA approves Botox injections to treat pediatric patients with both upper and lower limb spasticity, unless it was caused by cerebral palsy.
FDA Approves New HIV PrEP Drug
The FDA approves Descovy to reduce the risk of HIV infection through sex.
FDA Approves Duo of HIV Medications
HIV patients will be allowed to switch to doravirine or doravirine/lamivudine/tenofovir disoproxil fumarate if they are virally suppressed with no prior history of treatment failure.
Biden Cancer Initiative Suspended During Campaign
Former Vice President Joe Biden's presidential campaign has resulted in the nonprofit organization's indefinite suspension.
ALA, ATS Lung Cancer Screening Guide Could Save Thousands At Risk
Lung cancer is currently the deadliest cancer in the US. An online guide and tool provider for physicians could help cut the rate.
FDA Approves Hexavalent Vaccine for Children
Developed as part of a joint partnership between Sanofi and Merck, Vaxelis' commercial supply is not expected until 2020.
FDA Approves Romiplostim for Immune Thrombocytopenia
The therapy is indicated for ITP patients aged 1 year and older who have been diagnosed for at least 6 months, and have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy.
Norah Terrault, MD, MPH: Benefits of Avatrombopag for Thrombocytopenia
After the therapy was approved by the FDA in May, investigators are anticipating its first real-world data will paint a clearer picture of its potential.
W. Hayes Wilson, MD: Open-Label Trial of Repository Corticotropin Injection for Rheumatoid Arthritis
The smaller, incomplete study is looking into both the efficacy and safety of the longtime therapy for patients with RA.
W. Hayes Wilson, MD: The History of Repository Corticotropin
Repository corticotropin injection’s nearly six-decade history as a therapy has been tumultuous, but has most recently resulted in its use as an auto-immune drug.
Roy Fleischmann, MD: Hurdles to Optimizing RA Therapy
Speaking ambitiously, determining the right tests and initial therapies for patients with rheumatoid arthritis could become optimized.
Case Study: Subcutaneous Allergen Immunotherapy for Severe Atopic Dermatitis
A 48-year-old man presents with severe atopic dermatitis that he’s had since childhood. Can allergy shots succeed where standard treatments failed?
Nonalcoholic Fatty Liver Disease May Be Underappreciated Comorbidity Among People With HIV
Research on nonalcoholic fatty liver disease in persons infected with HIV revealed a prevalence of the condition of about 40%.
Advancing Non-Invasive Treatment Options for Endometriosis
Medical options can include oral contraceptives, pain medications, hormonal therapies, and gonadotropin-releasing hormone (GnRH) agonists.
Q&A: Jane Armitage, FRCP, FFPH, on the ASCEND Trial Results for Aspirin Benefits
How the conflicting results of the ASCEND trial are actually much more determinant than they appear, and critical in the scope of treating comorbidities in patients with diabetes.
Q&A: From Practicing Pulmonologist to Researching Treatment Options
Frank Trudo, MD, MBA, was recently appointed as VP, US Respiratory, Medical Affairs, at AstraZeneca.
FDA Roundup: New Non-Narcotic for Opioid Withdrawal
Catch up on this week's biggest headlines in FDA news.
FDA Roundup: Nasal Spray for Gastroparesis in Women
This week, the FDA received an application for a metoclopramide nasal spray and a receptor agonist for hypoactive sexual desire disorder, approved baricitinib on its second try, and granted Priority Review to emicizumab for hemophilia A.
UNC Global Health Podcast Series: HIV Matters
This podcast series details the ins and outs of managing, preventing, and treating HIV, from the perspective of the faculty and patients of the UNC Institute for Global Health & Infectious Diseases.
MDNN: Cinnamon-Flavored E-Cigarettes, Hypertension Prevalence, Right-to-Try Law
This week on MDNN: Cinnamon flavoring in e-cigarettes has been found to disrupt the lungs’ anti-bacterial defense system, new hypertension guidelines have increased the condition's prevalence, and the US Congress passed a right-to-try bill.
MDNN: ADHD and Eating Disorders, Opioid Funding, Overworked Nurses
This week on MDNN: ADHD symptoms are linked to binge and restrictive eating, physicians paid by opioid marketers are more likely to prescribe them, and one-third of nurses work overtime.
Vivek Patel, MD: Retinal Pathology and Alterations in the Brain
Researchers are using hi-def retinal and neuroimaging techniques to elucidate the relationship between pathology in layers of the retina and downstream brain alterations.
MDNN: Physician Stigmatizing, Pokemon GO, Depression by Gender, and Fast Food Fertility
This week on MDNN: Stigmatizing phrasing influences patient care, Pokemon GO improves behavioral health, depressed women and men differentiate in gene expression, and fast food can stall a woman's time to pregnancy.
MDNN: ASD Rates Going Up, Hand Washing for C. Diff, and PROMISE 1 Results
This week on MDNN: Autism Spectrum Disorder rates are rising in the US, handwashing is effective for C. diff prevention, and PROMISE 1 trial results have been reported.
MDNN: Acetaminophen Linked to ADHD, ASD, New DMT Recommendations for MS, and Resources for Managing Burnout
This week on MDNN: Prolonged use of acetaminophen has been linked to an increase in the relative risk of ADHD and ASD, the ANA annual meeting issued 30 new recommendations for disease-modifying therapy for multiple sclerosis and the American Academy of Family Physicians announced a new Well-Being Planner to manage stressors and address burnout.
MDNN: Transgender Mental Health, Opioid Addiction, and Type 1 Diabetes in Food Swamps
MDNN: Postive Results for Upadacitinib, HIV Testing for Older Adults, and US Disease Trends
This week on MDNN: The SELECT-COMPARE trial reported positive results for upadacitinib, older adults in the US are not being tested for HIV, and the shifting trends in US mortality.
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