BRAF Mutation Emerging as Prognostic in KRAS Wild-Type CRC Patients
Colorectal cancer patients who had wild-type (normal) KRAS gene status, but mutations in the BRAF, had a poor prognosis in spite of treatment with cetuximab.
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Polyamines in the Diet Related to High-Risk Adenomas
Patients with high intake of polyamines found in orange juice, corn, red meat, peas and nuts had larger, more advanced adenomas on colonoscopy screening.
IGF Receptor Antagonist Shows Activity in Advanced Pancreatic Cancer
For patients with pancreatic cancer, an inhibitor of the insulin-like growth factor receptor led to response rates or stable disease in a majority of patients.
TN Disease Category Impacts Outcomes in Anal Cancer Patients
The TN category of disease significantly impacts survival, relapse, and colostomy failure in patients with anal cancer treated with concurrent chemoradiation.
Sorafenib Benefits All Advanced HCC Subgroups but Not After TACE
Sorafenib was beneficial in advanced hepatocellular carcinoma patients, but failed to improve outcomes when given after transarterial chemoembolization.
Transhiatal Bests Left Thoracoabdominal for Some Esophogastric Tumors
Resection via the abdominal and transhiatal approach is superior to the left thoracoabdominal approach for cardia and subcardia tumors.
What's the Meaning of Positive Peritoneal Cytology in Gastric Cancer
Gastric cancer patients with positive peritoneal cytology who convert to negative cytology after systemic chemotherapy see a great improvement in survival.