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Amiodarone use and permanent pacing for atrial fibrillation: Are there differences between the sexes?

Among patients with atrial fibrillation, amiodarone (Cordarone, Pacerone) is the most useful drug for the preservation of sinus rhythm.1-3 Although amiodarone carries a well-known risk of potentially serious noncardiac toxicities, perhaps less well recognized is its major cardiovascular side effect of bradycardia.

New Framingham Heart Study global cardiovascular risk instruments: Helping physicians optimize their patients' cardiovascular care

While most patients are concerned about their risk for myocardial infarction, it is important to remember that the risk factors for death from all cardiovascular diseases, including stroke, peripheral arterial disease, and coronary artery disease, are similar.

Prediction of coronary artery disease in patients with diabetes and albuminuria

We developed a set of equations to predict the risk or probability of developing coronary artery disease (CAD) in 10 years among American Indians. The equations are based on the significant risk factors identified in the Strong Heart Study, a longitudinal study of cardiovascular disease in American Indians. The equations can be used in patient education and to evaluate the efficacy of CAD prevention and intervention programs.

Never too old for statins

Elderly patients with a history of an acute coronary syndrome (ACS) are at higher risk for subsequent cardiovascular events than younger patients.

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Noninvasive assessment of coronary artery bypass grafts with 64-slice computed tomographic angiography

We evaluated the accuracy of the 64-slice computed tomography (CT) angiography scanner in subjects who were scheduled to undergo invasive angiography for possible stenosis in coronary artery bypass grafts. Results showed that the improved resolution of CT scanners with 64-slice technology allowed for a precise delineation of bypass graft occlusion or stenosis. It permitted an accurate noninvasive assessment of bypass grafts, even in subgroups of subjects with suboptimal scan conditions, such as those with arrhythmias or higher heart rates.

New Framingham Heart Study global cardiovascular risk instruments: Helping physicians optimize their patients' cardiovascular care

While most patients are concerned about their risk for myocardial infarction, it is important to remember that the risk factors for death from all cardiovascular diseases, including stroke, peripheral arterial disease, and coronary artery disease, are similar.

What Should I Do With This Abnormal ALT?

You see a 48-year-old white man for his annual examination. . The patient is overweight with a body mass index (BMI) of 32. A screening chemistry panel is normal except for an aspartate aminotransferase (AST, formerly SGOT) level of 85 U/L (normal 15-50 U/L) and an alanine aminotransferase (ALT, formerly SGPT) level of 98 U/L (normal 5-50 U/L). He says you are the first doctor he has seen in more than 10 years and does not recall the last time he had a blood test.

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How do cardiac and noncardiac conditions affect survival after ICD implantation?

The benefits of implantable cardioverter-defibrillators (ICDs) have been shown in randomized clinical trials. The factors that affect the risk–benefit ratio in a community setting, however, have not been evaluated.

Renal dysfunction in older age groups and mortality after acute myocardial infarction

Multiple observational and randomized trials support the finding that renal insufficiency has a significant, independent, graded effect on the risk of cardiovascular events and cardiovascular mortality.