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Intracranial hemorrhage in atrial fibrillation: Is there a racial/ethnic difference?

We evaluated a multiethnic cohort of subjects with nonrheumatic atrial fibrillation hospitalized over a 6-year period to determine the racial and ethnic differences in the risk of intracranial hemorrhage (ICH) and the effect of warfarin treatment on ICH risk. Treatment with warfarin was associated with a 2-fold greater risk of ICH in whites, a 4- to 5-fold greater risk in both blacks and Hispanics, and a 15-fold greater risk in Asians. After adjusting for established stroke risk factors and warfarin use, Asians were 4 times as likely as whites to have ICH, whereas blacks and Hispanics were twice as likely.

Low cholesterol, statins, and cancer risk: Déjà vu all over again

There has been an epidemiologic association of low total cholesterol levels with increased risk of cancer noted for several decades.

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Social Media Spotlight: Clinical Reader

The aim of Clinical Reader is to "bring academic content together and create a semantic digital medical library" by building a "user-friendly platform that will enable medical professionals around the world...to easily interact with the latest developments in their respective specialties." Clinical Reader CEO and founder Allan C. Marks, MD, explains the origins of the site, what he has planned for the future of Clinical Reader, and more.

Rivastigmine Patch Shows Global Benefit in Severe Alzheimer's Disease

Patients with advanced Alzheimer's disease treated with 13.3 mg rivastigmine patch showed greater improvements in cognitive, functional, and behavioral performance from baseline compared to patients who received 4.6 mg patches.

How Supplemental Newborn Screening Could Improve Patient Care

Genetic testing for medical conditions can be controversial, especially when it concerns newborns. Alan Copperman, MD discusses why the benefits outweigh the concerns.

Wedding Bell Money Blues

Even though the recession has cut into the average cost of a wedding, it has also hurt the ability of people to pay for it. If you're footing the bill, here are a few strategies for reducing the per-plate cost.

Pfizer's Innovative Oncology Division Is Right on Target

At the 101st American Association for Cancer Research (AACR) Annual Meeting in Washington, DC, in April, Pfizer presented a broad overview of its current oncology pipeline.

Perspectives from the office & beyond: A Visit to the Charleston Tea Plantation

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Syncope from ventricular tachycardia secondary to methadone use

Methadone HCI (Diskets, Dolophine, Methadose) is a synthetic opioid that has been used widely in the United States for the management of heroin addiction Treatment of opioid dependence has been shifting gradually from the older US Food and Drug Administration (FDA) inspection program, ...

Leveraging Telemedicine During the COVID-19 Outbreak

Telemedicine platforms can be used to monitor symptoms remotely and reduce overcrowding in healthcare facilities.

Of Doctors, Kids, and Careers