Medical Websites ~ AAN Guideline Evaluates Treatments for Muscle Cramps

The American Academy of Neurology's new guideline recommends that the drug quinine should be avoided for the treatment of routine muscle cramps "due to uncommon but serious side effects."

The American Academy of Neurology’s new guideline recommends that the drug quinine should be avoided for the treatment of routine muscle cramps “due to uncommon but serious side effects.” The guideline was published in the academy’s medical journal Neurology, in February. “Quinine should be considered only when cramps are very disabling, when no other drugs relieve the symptoms, and when side effects are carefully monitored,” according to the lead guideline officer, Hans D. Katzberg, MD. In addition, naftidrofuryl, diltiazem, and vitamin B complex may be alternatives; more research is needed.