
Early data suggest varenicline may improve abdominal pain, bloating, and bowel symptoms in patients with IBS.

Ayah Matar, MD, is a postdoctoral researcher at Mayo Clinic.

Early data suggest varenicline may improve abdominal pain, bloating, and bowel symptoms in patients with IBS.

Late-breaking ACG 2025 data link rimegepant to increased rectal compliance and reduced rectal sensation in IBS without constipation.