Subcutaneous Infusion of Levodopa, Carbidopa Effective Against Parkinson's "Off" Time
The method alleviates the 2 drugs' strained efficacy over time during Parkinson's progression.
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New Botulinum Neurotoxin Controls Cervical Dystonia
RT002 could treat moderate to severe isolated cervical dystonia with 2 or fewer annual shots.
Oral Levodopa for Parkinson's Motor Symptoms Reaches Trial Endpoints
Investigational levodopa form CVT-301 improves "off" period motor function.
Safinamide Improved Motor, Non-Motor Symptoms of Parkinson's Disease in Post Hoc Analysis of Trial Data
An Italian team presented its research on the topic at the 2017 International Congress of Parkinson’s Disease & Movement Disorders Conference.
Parkinson's Psychosis Study: Pimavanserin Reduced Symptoms in Cognitively Impaired at Least as Much as in Cognitively Normal
Psychosis and dementia are major risk factors for Parkinson's patients.
Weighing Treatments for Levodopa-Related Motor Fluctuations, Dyskinesias
An expert offers insights on levodopa-induced motor complications in Parkinson’s disease.
Expert Shares a Reasoned Approach to Diagnosing and Treating Choreas
The first step in successfully treating chorea is making the correct diagnosis.
Medical Treatments for Dystonia Expand into New Territory
Specific dystonia cases require specific treatments.
Valbenazine for Tardive Dyskinesia: A Case Study in Ensuring Rapid FDA Approval
Blinded rating of remotely monitored patients supported the drug’s efficacy.
Systematic Review of Valbenazine Shows Its Efficacy
A deeper look a the sole FDA-approved treatment for Tardive Dyskinesia.
Resveratrol-based Nutraceutical Improved Dark Adaptation in Patients with Vision Loss from AMD
Dark adaptation screening plus Longevinex could alter the course of the disease.
Study Finds 25% of Patients with AMD Remain Undiagnosed After Dilated Eye Exam
Of those undiagnosed, 30% had large drusen at the time.
Early Detection of Choroidal Neovascularization in AMD Could Improve Visual Outcomes
The typical nAMD patient loses lines of vision before being diagnosed.
Aflibercept Vs. Ranibizumab: Similar QOL Benefits, Varied Costs for Treating Diabetic Macular Edema
Incremental ratio was too high even with most favorable scenario for aflibercept.
Ranibizumab for DME: A Pooled Analysis of Clinical Trials of its Vascular Safety
Vascular death was 2.5 times more common with 0.3 mg ranibizumab than with sham.
Study Explores Risk Factors for RA-Associated Interstitial Lung Disease
Factors include elevated carbohydrate antigen 125 and lactate dehydrogenase.
Case Report Supports the Role of NF-κB Activation in Antigen-B27 Uveitis
Serum levels of ubiquitin and proteasome correlated well with uveitis score.
AMD Treatment Still Brings Anxiety, Depression Despite Visual Improvements
Reassurance should focus on success rates and low risk of serious problems.
MONARCH Trial: Sarilumab Outperformed Adalimumab for RA After 6 Months as Monotherapy
Sarilumab patients had less disease activity and pain, greater response rates.
Small Case Series: Bevacizumab Did Not Improve Acuity in Behçet's-Related Macular Edema
Though fluorescein angiograms of treated eyes did show reduction in disc leakage.
Ranibizumab for DME: Short-Term Effects on Foveal Thickness Predict Visual Acuity Changes
Foveal thickness 2 hours post-injection correlated with acuity 1 month later.
Study Supports Using Ethnicity-Based Strategies for Delaying the Onset or Progression of AMD
AMD negatively affected vision-specific function in Chinese but not others.
ADA's Position Statement Advises on Role of Anti-VEGF Agents in DME
For eyes 20/50 or worse, aflibercept most effective at improving visual acuity.
Large AMD Study Associates Frequent Bevacizumab Injections with Risk of Glaucoma Surgery
Glaucoma surgery 2.5 times more likely after 7 or more shots in a year than after 3.
Large Study Finds Bilateral Anti-VEGF Injection on Same Day Appears Safe
Acute intraocular inflammation was less common for ranibizumab than aflibercept.
Uveitic Glaucoma: Intensive Treatment Necessary Following Trabeculectomy
Uveitis recurrence was associated with failure of trabeculectomy, not implant.
Determining the Role of Stress in the Progression of AMD
Perceived Stress Scale worked well in assessing stress levels of AMD patients.
Refractory Noninfectious Uveitis: Orphan IMT Drugs Hold Promise
Review explores reducing corticosteroid use with immunomodulatory therapies.
Unilateral nAMD Without Drusen in Other Eye: A Distinct Clinical Entity?
Two-year retrospective study indicates need to tailor treatment strategy.
Study Finds Population Differences Between Randomized Controlled Trials, Real-World Studies of Ranibizumab
DME patients in non-interventional studies notably older than in RCTs.