Treat-and-Extend Regimen Proves Preventive of Long-Term Vision Loss in AMD
These regimens can also ensure the maintenance of visual acuity levels that can keep patients self-sufficient in real-world scenarios, such as driving, reading, and recognizing faces.
Ranibizumab Shows Improved Outcomes for Patients with Concurrent DME, Macular Nonperfusion
Despite having worse vision and more CST than participants without baseline MNP upon entering the trials, patients experienced increased visual acuity along with improvements in anatomy.
NSAIDs May Reduce Incidence of Macular Edema Following Cataract Surgery
Researchers aimed to determine how prophylactic, topical NSAIDs affected the development of CME, specifically ketorolac tromethamine 0.4% and nepafenac 0.1%.
Psychological Distress and Socioeconomic Status Can Affect Risk for Chronic Diseases
There was a dose-response pattern of psychological distress associated with significantly increased risk for COPD, cardiovascular disease, and arthritis.
Socioeconomic Status Affects Discrimination, Depression in African American Youth
The youths’ perception of discrimination was related to a higher risk of MDD over the course of 30 days, then at 12 months, and then over the course of their lifetimes.
Specific Features in Mood Disorders May Affect Outcome of Ketamine Treatment
Response to ketamine treatment in mood disorders may be better predicted based on baseline cognitive impairment.
Human Umbilical Tissue-Derived Cell Treatment Benefits Patients with AMD
Researchers examined the role of RPE dysfunction in patients with AMD and found this discovery demonstrated hUTC’s potential therapeutic value in the treatment of AMD.
DEX Implant Only Temporarily Effective in DME Treatment
While DEX implants improved BCVA in patients with DME, new data shows the improvement diminished over time.
TRP with Ranibizumab Fails Improve DME Visual Outcome, Treatment Burden
Researchers found no evidence that adding targeted retinal photocoagulation to ranibizumab treatment improved visual outcomes, decreased treatment burden, or reduced demand for anti-VEGF therapy
Dysregulation of Anti-Sense Transcription Revealed in Eye Tissues with Macular Degeneration
According to the investigators, this is the first time a consistent and dramatic global effect on antisense transcription has been associated with a disease state in humans.
Seeking Various Vulnerabilities in Regional Areas of the Human Retina
Foveomacular, juxta-macular, and peripheral retina punch biopsies can be used to determine protein levels and identify patterns of expression.
CNV Removal Improves Complications with Anti-VEGF Therapy for AMD
While not the preferred solution, choroidal neovascularization removal in patients with AMD can be useful in specific circumstances.
Self-Rated Functional Measures Informative for Inadequate Response Patients with MDD
Following their review, the authors concluded that the SDS reports are useful in informing acute randomized placebo-controlled studies.
Nicotine Dependence Risk is Higher in Patients with Major Depressive Disorder
Roughly 41% of those diagnosed with psychiatric illness were also smokers, and they were 70% more likely to be smokers than their counterparts without psychiatric illness.
Low Luminance Questionnaire Linked to Functional Measures of AMD
Computerized low luminance visual acuity and low luminance deficit in patients with early/intermediate age-related macular degeneration were linked to LLQ scores.
Safety, Tolerability Increases Post-Bevacizumab Injection in Intraocular Pressure
New research has shown that increased IOP is tolerable to corneal endothelium, and safe for most patients’ eyes despite immediate increases post-injection.
Putamen Volume Rates Vary Due to Age and Depressive Symptoms in the Elderly
The rate of reward center volume loss may vary between nondepressed individuals and depressed individuals across multiple age groups.
What's Next in Clinical TMS Study for PTSD, MDD
Transcranial magnetic stimulation, which was approved by the FDA for drug-resistant depression in 2009, has recently experienced a growth in clinical use.
Depression and Anxiety Symptoms in Midlife Women Vary with Menopausal Status
During perimenopause, women are more likely to experience symptoms of depression, and during postmenopause, they are more likely to experience anxiety symptoms.
Patients with AMD Receiving Injections Impacted by Expectation, Psychosocial Issues
32% of patients said they were going to stop treatment and decline further injections due to mismanaged expectations of discomfort and anxiety.
BVCA Gains Maintained with Fewer Ranibizumab Injections with DME
After receiving an average of 4.7 injections through year 1, patients received 0.9 injections in year 4, while maintaining gains in BCVA letters.
Color Doppler Imaging Determines Risk, Biomarkers in AMD
Color Doppler imaging showed that patients with AMD had general vascular disorder in all arteries evaluated.
Gestational Diabetes Influences Cardiovascular Disease Risk in Women
Women who had experienced gestational diabetes were at a 43% higher risk for CVD events, such as myocardial infarction or stroke.
Glycemic Control in Patients with T2D Linked to Risk of CV Events
The real-world data revealed a U-shaped relationship between glycemic control and CV disease risk, according to the authors.
Water Baths as Effective as Bleach Baths for Atopic Dermatitis
The study provides a blueprint for improving future bleach bath studies.
CGM Influences Hyperglycemia Risk for Pregnant Women with T1D
Continuous glucose monitoring was shown to lower the risk of hyperglycemia compared to capillary glucose monitoring alone.
Electronic Glycemic Management Improves Outcomes for Diabetics
Average daily blood glucose during the study was 152 mg/dL, down from 71 mg/dL - or 32% - from the average admission blood glucose, and below the goal range.
Dolutegravir Maintenance Therapy for HIV
The focus must switch to the more promising dual-therapy options like dolutegravir and lamivudine or rilpivirine.
Single-tablet Alternative for HIV-1 Patients
The single tablet is an effective potential alternative treatment option for the management of virologically suppressed patients with HIV.
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