Jonathan Alicea

Children treated with SSRIs and SGAs concurrently demonstrate higher waist circumference, BMI, and plasma total cholesterol compared to those on monotherapy.

Overweight/obese patients with elevated fasting blood glucose generally present with higher degrees of insulin resistance, inflammation, adverse cardiovascular disease risk profile.

Data presented at ADA 2021 supports the noninferiority of faricimab to aflibercept.

Patients on placebo with a history of systemic non-steroidal immunosuppressants generally fared worse than their treatment-naïve counterparts.

The approval was supported by 2 trials demonstrating treatment efficacy in reducing ocular itching and inflammation in the cornea.

Stephen Russell, MD, talks about promising new data that has the potential to provide a breakthrough for treating the most common mutation of the rare genetic eye disease.

Among 49,197 vaccinated employees at Mass General Brigham, 776 self-reported cutaneous reactions following the first dose.

These results highlight the importance of interventions to address modifiable behaviors and risk factors for these patients.

Epiretinal membrane and initial detachment of the macula are risk factors for post-operative CME.

Patients with chronic kidney disease reported poor quality of life, particularly in domains related to their condition.

This past year has brought unique challenges for sickle cell disease patients and communities of color. The ongoing vaccination campaign is yet another challenge that healthcare communities must find ways to overcome.

A sickle cell expert reflects on the state of care and access for sickle cell communities.

A personalized topical cream applied for 1 week was shown to reduce Staphylococcus areus colonization and improve clinical outcomes.

Improvements in neovascularization and best-correct visual acuity were generally not sustained following treatment discontinuance.

Older age, macroalbuminaria, and high diastolic blood pressure are among some of the risk factors significantly associated with onset of chronic kidney disease.

Adding platelet-rich plasma to narrowband–ultraviolet B is likely a safe, effective, and efficient means of treating atopic dermatitis.

More frequent testing and reduction of the rate of progression as the end point may allow investigators to more efficiently assess efficacy of glaucoma therapy.

The dual orexin receptor antagonist notably demonstrates a positive benefit-risk balance for patients

More studies are needed to determine whether bi-level positive airway pressure ventilation can help prevent acute chest syndrome.

Data from the large-scale, population-based study corroborate previous single-center study findings.

Dapagliflozin and the SGLT2 inhibitor class may have untapped potential far beyond the reduction of heart failure hospitalization risk.

A systematic review of clinical trials notes that topical eye drops may lead to favorable retinal and visual outcomes, despite heterogeneity across multiple studies.

The COVID-19 pandemic had forced vitiligo patients to delay treatments; however, not much is known about the effects of delaying on disease course.

COVID-19 severity should be looked at in the context of pre-existing comorbidities, age, social determinants, and bias among data sources.

Misha Rosenbach, MD, gives an overview of climate change and its relevance to dermatology.

Treatment with plasminogen, human-tmvh was associated with improvements in existing lesions and prevention of new lesions in supporting data.

There are no guidelines on sickle cell patient referral to pulmonologists, associated outcomes, and best therapeutic interventions.

Jordana Hoppe, MD, highlights some key points about the genetic condition.

Meaningful change thresholds in POEM and DLQI scores have been established for adolescents and adults.

A panel of retinal experts developed definitions for and classified the reasons behind patient nonadherence and nonpersistence.