Luke Laffin, MD

Luke Laffin, MD, is the co-director of the Center for Blood Pressure Disorders, medical director of cardiac rehabilitation, and associate professor of medicine at Cleveland Clinic.

Articles by Luke Laffin, MD

Luke Laffin, MD | Image Credit: Cleveland Clinic

Tonlamarsen Produces Persistent, Long-Term Angiotensin and BP Improvements

ByLuke Laffin, MD

September 14th 2026

Luke Laffin, MD, discusses his secondary analysis of the phase 2 KARDINAL trial, which demonstrated substantial improvements in uncontrolled hypertension.

Gene Editing for Lipids: 1-Year CTX310 Data, With Luke Laffin, MD

ByLuke Laffin, MD

August 30th 2026

Luke Laffin, MD, discusses 1-year data showing CTX310 produced durable reductions in ANGPTL3, LDL cholesterol, and triglycerides.

Tonlamarsen Lowers Angiotensinogen, Mixed Results for Blood Pressure, With Luke Laffin, MD

ByLuke Laffin, MD

April 3rd 2026

Laffin discusses results from the Kardinal study, which investigated a single dose of tonlamarsen followed by placebo against monthly tonlamarsen treatment in hypertension.