
Marlyn Mayo, MD, discusses long-term seladelpar data linking IL-31 reductions to PBC pruritus improvement and why the cytokine is not ready to guide treatment.

Marlyn Mayo, MD, is a professor of internal medicine at UT Southwestern Medical Center.

Marlyn Mayo, MD, discusses long-term seladelpar data linking IL-31 reductions to PBC pruritus improvement and why the cytokine is not ready to guide treatment.

Marlyn Mayo, MD, discusses 4-year ELATIVE data on elafibranor sustaining biochemical response across PBC stages, with stable fibrosis markers.

Mayo explains findings from a pooled analysis of pruritus data from RESPONSE and ENHANCE highlighting seladelpar’s impact on itch in PBC.

Mayo explains current shortcomings of pruritus care in PBC and what the additions of elafibranor, seladelpar, and other agents in development may offer.

November 6th 2026