Authors

Study Suggests Correlation Between Atopic Dermatitis and Serum Clusterin Levels

Researchers have reported that higher serum clusterin levels in children may be linked with atopic dermatitis symptom, potentially providing a candidate molecule to reflect disease’s severity.

The Virtual Window: Clinical Trial Reports--March 2007

Successful research into new therapies for cancer requires a ready supply of patients willing to participate in clinical trials, and physicians and other health care professionals who will refer their patients to the appropriate studies. In each issue, we provide up-to-date information on current or recently announced phase I, II, and III clinical trials focused on biotech-related oncology pharmaceutical therapies.

Take a Hike, or Better Yet, Take a Trek

Procainamide-induced Pleural and Pericardial Effusions

Drug-induced diseases and serious adverse drug effects can alter therapeutic plans and greatly affect patient outcomes. Many medications are known to have a narrow therapeutic index and to require close patient monitoring.

Tasmania: Enjoy Holidays Aussie-Style

Court Orders Gilead to Pay Merck in Hepatitis C Drug Patent Lawsuit

Merck just got $2.54 billion richer with the ruling of a federal jury.

Spray Bear Repellent on Your Portfolio

Severe Illness in Children: "Could This Be Sepsis?"

As providers, we do not want to scare parents into worrying about every cough or fever. Not every illness is sepsis.

Real-World Challenges to Prescribing Sacubitril/Valsartan for Patients with Heart Failure

Patient selection, proper up-titration, and insurance barriers must be considered by cardiologists and other physicians seeking to treat patients with the new combo medication.

Pharmacotherapy for Obesity: Is There a Magic Bullet?

Can Economic Reports Foretell a Recession?

The Cardiovascular Safety of Incretin-Based Therapies

A review of the cardiovascular safety and potential benefits of incretin-based therapies for patients with type 2 diabetes mellitus.

Endovascular Repair of Splenic Artery Aneurysm

Splenic artery aneurysm is the most common form of visceral artery aneurysm. Most present asymptomatically with incidental findings on CT or ultrasound which are diagnostic, although about 20% present with vague left upper quadrant abdominal pain. Treatment should be aimed at preserving splenic function whenever possible and endovascular treatments offer a less invasive option to patients than open surgical ligation or resection.

New Hope for Young Children with SMA - Early Treatment is Key

Until recently, there's been little providers or parents could do, beyond offering supportive care, to improve outcomes for children with SMA. But there is new hope.

Antithrombotic treatment of high-risk elderly patients hospitalized with atrial fibrillation

We assessed the pattern of use and the effectiveness of antithrombotic therapy in a cohort of high-risk elderly patients hospitalized for atrial fibrillation, with data derived from prescription, hospitalization, and mortality databases from 3 linked registries. Results showed that antithrombotic therapy was underused, even in patients with no comorbid conditions. In addition, patients exposed to antithrombotic therapy had a significantly lower mortality rate. The collection of epidemiological data by record linkage represents a flexible and readily available tool for monitoring and improving routine clinical care.

Combining warfarin and antiplatelet therapy after coronary stenting

We conducted an observational study to compare singleantiplatelet therapy with dualantiplatelet therapy among patients requiring long-term warfarin therapy after coronary stenting. Results showed that there was no difference in mortality or myocardial infarction between the 2 treatment regimens at 6 months, with no excess in-hospital bleeding; however, larger trials are needed to determine firm recommendations.